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Adgrl2 adhesion G protein-coupled receptor L2 [ Mus musculus (house mouse) ]

Gene ID: 99633, updated on 18-Apr-2024

Summary

Official Symbol
Adgrl2provided by MGI
Official Full Name
adhesion G protein-coupled receptor L2provided by MGI
Primary source
MGI:MGI:2139714
See related
Ensembl:ENSMUSG00000028184 AllianceGenome:MGI:2139714
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lec1; Gm619; Lphh1; Lphn2; CIRL-2; mKIAA0786
Summary
Predicted to enable G protein-coupled receptor activity and PDZ domain binding activity. Involved in synapse organization. Acts upstream of or within positive regulation of synapse assembly and response to bacterium. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Is expressed in heart. Orthologous to human ADGRL2 (adhesion G protein-coupled receptor L2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 41.1), CNS E14 (RPKM 39.9) and 20 other tissues See more
Orthologs
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Genomic context

Location:
3 H3; 3 74.1 cM
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (148521491..149150832, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (148815586..148989096, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_09250 Neighboring gene predicted gene, 29836 Neighboring gene STARR-seq mESC enhancer starr_09251 Neighboring gene predicted gene, 23131 Neighboring gene STARR-seq mESC enhancer starr_09252 Neighboring gene STARR-positive B cell enhancer mm9_chr3:148154297-148154597 Neighboring gene STARR-seq mESC enhancer starr_09253 Neighboring gene STARR-positive B cell enhancer mm9_chr3:148358491-148358791 Neighboring gene STARR-seq mESC enhancer starr_09254 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:148515580-148515781 Neighboring gene STARR-seq mESC enhancer starr_09255 Neighboring gene STARR-seq mESC enhancer starr_09256 Neighboring gene STARR-seq mESC enhancer starr_09257 Neighboring gene predicted gene, 30827 Neighboring gene STARR-seq mESC enhancer starr_09259 Neighboring gene STARR-seq mESC enhancer starr_09260 Neighboring gene predicted gene, 25127 Neighboring gene predicted gene, 30575 Neighboring gene STARR-seq mESC enhancer starr_09264 Neighboring gene STARR-seq mESC enhancer starr_09265 Neighboring gene STARR-positive B cell enhancer ABC_E337 Neighboring gene predicted gene 10287 Neighboring gene STARR-positive B cell enhancer mm9_chr3:149002145-149002445 Neighboring gene predicted gene, 57703 Neighboring gene predicted gene 1653 Neighboring gene RIKEN cDNA A630039O03 gene Neighboring gene STARR-positive B cell enhancer mm9_chr3:149073444-149073744 Neighboring gene STARR-positive B cell enhancer mm9_chr3:149108487-149108788 Neighboring gene predicted gene, 26468 Neighboring gene predicted gene 5149 Neighboring gene STARR-seq mESC enhancer starr_09268 Neighboring gene STARR-seq mESC enhancer starr_09269 Neighboring gene predicted gene, 31121 Neighboring gene STARR-seq mESC enhancer starr_09270 Neighboring gene predicted gene, 31244

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (7)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC38872

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables PDZ domain binding ISO
Inferred from Sequence Orthology
more info
 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in postsynaptic membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
adhesion G protein-coupled receptor L2
Names
G protein coupled receptor Lec1
calcium-independent alpha-latrotoxin receptor 2
calcium-independent alpha-latrotoxin receptor homolog 2
latrophilin 1
latrophilin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081298.2NP_001074767.1  adhesion G protein-coupled receptor L2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001074767.1

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
    Consensus CDS
    CCDS80059.1
    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    UniProtKB/TrEMBL
    A0A0G2JGM8
    Related
    ENSMUSP00000143626.2, ENSMUST00000197567.5
    Conserved Domains (8) summary
    smart00303
    Location:788840
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:469533
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:11281487
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:542764
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:850875
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:142398
    OLF; Olfactomedin-like domain
    cl28897
    Location:8491129
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. NM_001405986.1NP_001392915.1  adhesion G protein-coupled receptor L2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  3. NM_001405987.1NP_001392916.1  adhesion G protein-coupled receptor L2 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
    Related
    ENSMUSP00000142347.2, ENSMUST00000198779.5
  4. NM_001405988.1NP_001392917.1  adhesion G protein-coupled receptor L2 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  5. NM_001405989.1NP_001392918.1  adhesion G protein-coupled receptor L2 isoform 4 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  6. NM_001405990.1NP_001392919.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  7. NM_001405991.1NP_001392920.1  adhesion G protein-coupled receptor L2 isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  8. NM_001405992.1NP_001392921.1  adhesion G protein-coupled receptor L2 isoform 6 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  9. NM_001405993.1NP_001392922.1  adhesion G protein-coupled receptor L2 isoform 6 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
    Related
    ENSMUSP00000143444.2, ENSMUST00000195988.5
  10. NM_001405994.1NP_001392923.1  adhesion G protein-coupled receptor L2 isoform 7 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  11. NM_001405995.1NP_001392924.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
    UniProtKB/TrEMBL
    A0A0G2JDE3
  12. NM_001405996.1NP_001392925.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
    UniProtKB/TrEMBL
    A0A0G2JDE3
  13. NM_001405997.1NP_001392926.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
    UniProtKB/TrEMBL
    A0A0G2JDE3
    Related
    ENSMUSP00000142336.2, ENSMUST00000200543.5
  14. NM_001405998.1NP_001392927.1  adhesion G protein-coupled receptor L2 isoform 9 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  15. NM_001405999.1NP_001392928.1  adhesion G protein-coupled receptor L2 isoform 10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  16. NM_001406000.1NP_001392929.1  adhesion G protein-coupled receptor L2 isoform 10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  17. NM_001406001.1NP_001392930.1  adhesion G protein-coupled receptor L2 isoform 10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  18. NM_001406002.1NP_001392931.1  adhesion G protein-coupled receptor L2 isoform 10 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  19. NM_001406003.1NP_001392932.1  adhesion G protein-coupled receptor L2 isoform 11 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
    Related
    ENSMUSP00000143320.2, ENSMUST00000199750.5
  20. NM_001406004.1NP_001392933.1  adhesion G protein-coupled receptor L2 isoform 12 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  21. NM_001406005.1NP_001392934.1  adhesion G protein-coupled receptor L2 isoform 13 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  22. NM_001406006.1NP_001392935.1  adhesion G protein-coupled receptor L2 isoform 14 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  23. NM_001406007.1NP_001392936.1  adhesion G protein-coupled receptor L2 isoform 15 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  24. NM_001406008.1NP_001392937.1  adhesion G protein-coupled receptor L2 isoform 16 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  25. NM_001406009.1NP_001392938.1  adhesion G protein-coupled receptor L2 isoform 17 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  26. NM_001406010.1NP_001392939.1  adhesion G protein-coupled receptor L2 isoform 17 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
  27. NM_001406011.1NP_001392940.1  adhesion G protein-coupled receptor L2 isoform 17 precursor

    Status: VALIDATED

    Source sequence(s)
    AC113315, AC114679, AC138591
    Related
    ENSMUSP00000143788.2, ENSMUST00000196526.5
  28. NM_001406018.1NP_001392947.1  adhesion G protein-coupled receptor L2 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC110553, AC113315, AC114679, AC115737, AC138591
  29. NM_001406019.1NP_001392948.1  adhesion G protein-coupled receptor L2 isoform 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AC110553, AC113315, AC114679, AC115737, AC138591, AC161434
    UniProtKB/TrEMBL
    A0A0G2JDE3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    148521491..149150832 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163465.1XP_036019358.1  adhesion G protein-coupled receptor L2 isoform X28

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (8) summary
    smart00303
    Location:771823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:10871155
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8321088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  2. XM_036163464.1XP_036019357.1  adhesion G protein-coupled receptor L2 isoform X28

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (8) summary
    smart00303
    Location:771823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:10871155
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8321088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  3. XM_036163459.1XP_036019352.1  adhesion G protein-coupled receptor L2 isoform X23

    UniProtKB/TrEMBL
    A0A0G2JDF4
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9641312
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709965
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  4. XM_036163477.1XP_036019370.1  adhesion G protein-coupled receptor L2 isoform X40

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9641061
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709965
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  5. XM_036163462.1XP_036019355.1  adhesion G protein-coupled receptor L2 isoform X26

    UniProtKB/TrEMBL
    A0A0G2JG66
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9641280
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709965
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  6. XM_036163475.1XP_036019368.1  adhesion G protein-coupled receptor L2 isoform X38

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9641072
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709965
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  7. XM_036163471.1XP_036019364.1  adhesion G protein-coupled receptor L2 isoform X34

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9791087
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709980
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  8. XM_036163461.1XP_036019354.1  adhesion G protein-coupled receptor L2 isoform X25

    UniProtKB/TrEMBL
    A0A0G2JG66
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881293
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  9. XM_036163460.1XP_036019353.1  adhesion G protein-coupled receptor L2 isoform X24

    UniProtKB/TrEMBL
    A0A0G2JG66
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881304
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  10. XM_036163478.1XP_036019371.1  adhesion G protein-coupled receptor L2 isoform X41

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881054
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  11. XM_036163470.1XP_036019363.1  adhesion G protein-coupled receptor L2 isoform X33

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881096
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  12. XM_036163456.1XP_036019349.1  adhesion G protein-coupled receptor L2 isoform X20

    UniProtKB/TrEMBL
    A0A0G2JDF4
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9641329
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709965
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  13. XM_036163457.1XP_036019350.1  adhesion G protein-coupled receptor L2 isoform X21

    UniProtKB/TrEMBL
    A0A0G2JFF5
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9791327
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709980
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  14. XM_036163455.1XP_036019348.1  adhesion G protein-coupled receptor L2 isoform X19

    UniProtKB/TrEMBL
    A0A0G2JFF5
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881336
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  15. XM_036163439.1XP_036019332.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    Conserved Domains (8) summary
    smart00303
    Location:784836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:11241489
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:846871
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8451125
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  16. XM_036163447.1XP_036019340.1  adhesion G protein-coupled receptor L2 isoform X12

    UniProtKB/TrEMBL
    A0A0G2JG66
    Conserved Domains (8) summary
    smart00303
    Location:771823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:11021407
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8321103
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  17. XM_036163443.1XP_036019336.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A0G2JDF4
    Conserved Domains (8) summary
    smart00303
    Location:771823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:10871452
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8321088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  18. XM_036163452.1XP_036019345.1  adhesion G protein-coupled receptor L2 isoform X16

    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881353
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  19. XM_006502433.5XP_006502496.1  adhesion G protein-coupled receptor L2 isoform X7

    UniProtKB/TrEMBL
    A0A0G2JDF4
    Conserved Domains (8) summary
    smart00303
    Location:771823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:10871452
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8321088
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  20. XM_036163479.1XP_036019372.1  adhesion G protein-coupled receptor L2 isoform X42

    Conserved Domains (5) summary
    smart00303
    Location:157209
    GPS; G-protein-coupled receptor proteolytic site domain
    pfam02354
    Location:497862
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:1133
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:219244
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:218498
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  21. XM_036163446.1XP_036019339.1  adhesion G protein-coupled receptor L2 isoform X11

    UniProtKB/TrEMBL
    A0A0G2JFV3
    Conserved Domains (8) summary
    smart00303
    Location:705757
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:399463
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:10451410
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:472681
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:767792
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:7661046
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  22. XM_006502424.5XP_006502487.1  adhesion G protein-coupled receptor L2 isoform X2

    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    Conserved Domains (8) summary
    smart00303
    Location:784836
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:11241489
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538760
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:846871
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8451125
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  23. XM_036163438.1XP_036019331.1  adhesion G protein-coupled receptor L2 isoform X1

    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    Related
    ENSMUSP00000142405.2, ENSMUST00000199238.5
    Conserved Domains (8) summary
    smart00303
    Location:789841
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:470534
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:11291494
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:543765
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:851876
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:143399
    OLF; Olfactomedin-like domain
    cl28897
    Location:8501130
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  24. XM_036163458.1XP_036019351.1  adhesion G protein-coupled receptor L2 isoform X22

    UniProtKB/TrEMBL
    A0A0G2JDF4
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9641318
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709965
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  25. XM_036163454.1XP_036019347.1  adhesion G protein-coupled receptor L2 isoform X18

    UniProtKB/TrEMBL
    A0A0G2JFF5
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881342
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  26. XM_036163451.1XP_036019344.1  adhesion G protein-coupled receptor L2 isoform X16

    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881353
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  27. XM_030252947.1XP_030108807.1  adhesion G protein-coupled receptor L2 isoform X15

    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    Conserved Domains (7) summary
    smart00303
    Location:661713
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    cd14964
    Location:723748
    7tm_GPCRs; TM helix 1 [structural motif]
    pfam02354
    Location:10021366
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415637
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:7221002
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  28. XM_036163440.1XP_036019333.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    Conserved Domains (8) summary
    smart00303
    Location:771823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:11111476
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8321112
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  29. XM_030252944.2XP_030108804.1  adhesion G protein-coupled receptor L2 isoform X3

    UniProtKB/Swiss-Prot
    E9Q6C7, Q8BM90, Q8JZZ7
    Conserved Domains (8) summary
    smart00303
    Location:771823
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:465529
    HormR; Domain present in hormone receptors
    pfam02140
    Location:49129
    Gal_Lectin; Galactose binding lectin domain
    pfam02354
    Location:11111476
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:538747
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:833858
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:138394
    OLF; Olfactomedin-like domain
    cl28897
    Location:8321112
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  30. XM_036163472.1XP_036019365.1  adhesion G protein-coupled receptor L2 isoform X35

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9641061
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709965
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  31. XM_036163469.1XP_036019362.1  adhesion G protein-coupled receptor L2 isoform X32

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9641072
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709965
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  32. XM_036163474.1XP_036019367.1  adhesion G protein-coupled receptor L2 isoform X37

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9791076
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709980
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  33. XM_036163473.1XP_036019366.1  adhesion G protein-coupled receptor L2 isoform X36

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881085
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  34. XM_036163468.1XP_036019361.1  adhesion G protein-coupled receptor L2 isoform X31

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881085
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  35. XM_036163476.1XP_036019369.1  adhesion G protein-coupled receptor L2 isoform X39

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881056
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  36. XM_036163467.1XP_036019360.1  adhesion G protein-coupled receptor L2 isoform X30

    UniProtKB/TrEMBL
    A0A0G2JH16
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9881096
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709989
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
  37. XM_036163453.1XP_036019346.1  adhesion G protein-coupled receptor L2 isoform X17

    UniProtKB/TrEMBL
    A0A0G2JDK6
    Conserved Domains (7) summary
    smart00303
    Location:648700
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00008
    Location:342406
    HormR; Domain present in hormone receptors
    pfam02354
    Location:9791344
    Latrophilin; Latrophilin Cytoplasmic C-terminal region
    pfam16489
    Location:415624
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cd14964
    Location:710735
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02549
    Location:15271
    OLF; Olfactomedin-like domain
    cl28897
    Location:709980
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_153517.1: Suppressed sequence

    Description
    NM_153517.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.