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ZBTB5 zinc finger and BTB domain containing 5 [ Homo sapiens (human) ]

Gene ID: 9925, updated on 5-Dec-2021

Summary

Official Symbol
ZBTB5provided by HGNC
Official Full Name
zinc finger and BTB domain containing 5provided by HGNC
Primary source
HGNC:HGNC:23836
See related
Ensembl:ENSG00000168795 MIM:616590
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 6.3), esophagus (RPKM 6.3) and 25 other tissues See more
Orthologs
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Genomic context

See ZBTB5 in Genome Data Viewer
Location:
9p13.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (37438102..37465450, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (37438099..37465447, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376035 Neighboring gene Sharpr-MPRA regulatory region 4136 Neighboring gene glyoxylate and hydroxypyruvate reductase Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 4 pseudogene 3 Neighboring gene potassium channel tetramerization domain containing 9 pseudogene 3 Neighboring gene RNA polymerase I subunit E Neighboring gene ribosomal protein L21 pseudogene 83

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014872.3NP_055687.1  zinc finger and BTB domain-containing protein 5

    See identical proteins and their annotated locations for NP_055687.1

    Status: VALIDATED

    Source sequence(s)
    AB002352, AL158155, AW075599, BC010007, DB457364
    Consensus CDS
    CCDS6610.1
    UniProtKB/Swiss-Prot
    O15062
    UniProtKB/TrEMBL
    Q5T942
    Related
    ENSP00000307604.4, ENST00000307750.5
    Conserved Domains (4) summary
    smart00225
    Location:25119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00017
    Location:615635
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:14119
    BTB; BTB/POZ domain
    pfam13465
    Location:627652
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    37438102..37465450 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005251634.2XP_005251691.1  zinc finger and BTB domain-containing protein 5 isoform X1

    See identical proteins and their annotated locations for XP_005251691.1

    UniProtKB/Swiss-Prot
    O15062
    UniProtKB/TrEMBL
    Q5T942
    Conserved Domains (4) summary
    smart00225
    Location:25119
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00017
    Location:615635
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:14119
    BTB; BTB/POZ domain
    pfam13465
    Location:627652
    zf-H2C2_2; Zinc-finger double domain
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