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RHOBTB1 Rho related BTB domain containing 1 [ Homo sapiens (human) ]

Gene ID: 9886, updated on 1-Mar-2024

Summary

Official Symbol
RHOBTB1provided by HGNC
Official Full Name
Rho related BTB domain containing 1provided by HGNC
Primary source
HGNC:HGNC:18738
See related
Ensembl:ENSG00000072422 MIM:607351; AllianceGenome:HGNC:18738
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Expression
Broad expression in placenta (RPKM 10.3), kidney (RPKM 7.3) and 22 other tissues See more
Orthologs
NEW
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Try the new Transcript table

Genomic context

See RHOBTB1 in Genome Data Viewer
Location:
10q21.2
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (60860860..61001967, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (61726193..61858729, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (62629196..62761198, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2389 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:62495900-62496400 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:62496401-62496901 Neighboring gene ANK3 divergent transcript Neighboring gene cyclin dependent kinase 1 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr10:62629619-62630120 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr10:62630121-62630620 Neighboring gene uncharacterized LOC124902432 Neighboring gene RNA, U2 small nuclear 72, pseudogene Neighboring gene uncharacterized LOC124902431 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2390 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2391 Neighboring gene uncharacterized LOC107984236 Neighboring gene Sharpr-MPRA regulatory region 5027 Neighboring gene uncharacterized LOC124902433 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3395 Neighboring gene MPRA-validated peak951 silencer Neighboring gene long intergenic non-protein coding RNA 845 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:62795847-62796395 Neighboring gene uncharacterized LOC124902434

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA0740, MGC33059, MGC33841

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in Cdc42 protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in establishment or maintenance of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endosome membrane TAS
Traceable Author Statement
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
rho-related BTB domain-containing protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242359.2NP_001229288.1  rho-related BTB domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001229288.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 and 4 encode the same protein.
    Source sequence(s)
    AB018283, BC032848, BU624790, DA830304
    Consensus CDS
    CCDS7261.1
    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  2. NM_001350902.2NP_001337831.1  rho-related BTB domain-containing protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AB018283, AK075129, BC041791, BQ574439
    Consensus CDS
    CCDS7261.1
    UniProtKB/Swiss-Prot
    O94844
    Related
    ENSP00000350595.4, ENST00000357917.4
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  3. NM_001350903.2NP_001337832.1  rho-related BTB domain-containing protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AB018283, AC011197, BE046002, BQ574439, DA859805, DR004641
    Consensus CDS
    CCDS7261.1
    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  4. NM_001350904.2NP_001337833.1  rho-related BTB domain-containing protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AB018283, BC032848, BU624790, BX389628, DA830304, DR002604
    Consensus CDS
    CCDS7261.1
    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  5. NM_001350905.2NP_001337834.1  rho-related BTB domain-containing protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AB018283, BC032848, BU624790, DA793865, DA830304, DR002604
    Consensus CDS
    CCDS7261.1
    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  6. NM_001350906.2NP_001337835.1  rho-related BTB domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AB018283, AC011197, AC027678, BE046002, BQ574439, DA859805, DR004641
    Conserved Domains (3) summary
    smart00225
    Location:276335
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:356461
    BTB; BTB/POZ domain
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  7. NM_001350907.2NP_001337836.1  rho-related BTB domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AB018283, AC027678, BQ574439, DA781491, DR004641
    Conserved Domains (3) summary
    smart00225
    Location:276335
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:356461
    BTB; BTB/POZ domain
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  8. NM_001350908.2NP_001337837.1  rho-related BTB domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AB018283, AC011197, AC027678, BE046002, BQ574439, DA859805, DR004641
    Conserved Domains (3) summary
    smart00225
    Location:276335
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:356461
    BTB; BTB/POZ domain
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  9. NM_001350909.2NP_001337838.1  rho-related BTB domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AB018283, AC027678, AI935070, BC032848, BQ574439, DA930841, DR004641
    Conserved Domains (3) summary
    smart00225
    Location:276335
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:356461
    BTB; BTB/POZ domain
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  10. NM_001350910.2NP_001337839.1  rho-related BTB domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AB018283, BC032848, BQ574439, DA930841, DR002604, DR004641
    Conserved Domains (3) summary
    smart00225
    Location:276335
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:356461
    BTB; BTB/POZ domain
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  11. NM_001350911.2NP_001337840.1  rho-related BTB domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AB018283, AC027678, BQ574439, DA793865, DA930841, DR004641
    Conserved Domains (3) summary
    smart00225
    Location:276335
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:356461
    BTB; BTB/POZ domain
    cl21455
    Location:187
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  12. NM_014836.5NP_055651.1  rho-related BTB domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_055651.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform. Variants 1-6 encode the same protein (isoform 1).
    Source sequence(s)
    AB018283, BC041791, BQ574439, DB453441
    Consensus CDS
    CCDS7261.1
    UniProtKB/Swiss-Prot
    O94844
    Related
    ENSP00000338671.5, ENST00000337910.10
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    60860860..61001967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047426080.1XP_047282036.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  2. XM_047426086.1XP_047282042.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  3. XM_047426099.1XP_047282055.1  rho-related BTB domain-containing protein 1 isoform X2

  4. XM_047426092.1XP_047282048.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  5. XM_024448271.2XP_024304039.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  6. XM_011540425.2XP_011538727.1  rho-related BTB domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    smart00174
    Location:17208
    RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
    smart00225
    Location:486583
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:476578
    BTB; BTB/POZ domain
    cl02518
    Location:406453
    BTB; BTB/POZ domain
  7. XM_011540424.2XP_011538726.1  rho-related BTB domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011538726.1

    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  8. XM_024448270.2XP_024304038.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  9. XM_047426083.1XP_047282039.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  10. XM_006718085.2XP_006718148.1  rho-related BTB domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006718148.1

    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  11. XM_047426088.1XP_047282044.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  12. XM_047426082.1XP_047282038.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  13. XM_047426077.1XP_047282033.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  14. XM_047426078.1XP_047282034.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  15. XM_047426098.1XP_047282054.1  rho-related BTB domain-containing protein 1 isoform X2

  16. XM_047426095.1XP_047282051.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  17. XM_047426087.1XP_047282043.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  18. XM_047426091.1XP_047282047.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  19. XM_024448272.2XP_024304040.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  20. XM_047426097.1XP_047282053.1  rho-related BTB domain-containing protein 1 isoform X2

  21. XM_047426094.1XP_047282050.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  22. XM_047426074.1XP_047282030.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  23. XM_017017002.3XP_016872491.1  rho-related BTB domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    smart00174
    Location:17208
    RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
    smart00225
    Location:486583
    BTB; Broad-Complex, Tramtrack and Bric a brac
    pfam00651
    Location:476578
    BTB; BTB/POZ domain
    cl02518
    Location:406453
    BTB; BTB/POZ domain
  24. XM_047426081.1XP_047282037.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  25. XM_047426096.1XP_047282052.1  rho-related BTB domain-containing protein 1 isoform X2

  26. XM_047426089.1XP_047282045.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  27. XM_047426090.1XP_047282046.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  28. XM_047426084.1XP_047282040.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  29. XM_047426075.1XP_047282031.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  30. XM_047426076.1XP_047282032.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  31. XM_047426093.1XP_047282049.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  32. XM_017017000.3XP_016872489.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  33. XM_047426079.1XP_047282035.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  34. XM_024448273.2XP_024304041.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    cd18355
    Location:248460
    BTB1_POZ_RHOBTB1; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18358
    Location:465590
    BTB2_POZ_RHOBTB1; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
    cd18530
    Location:593692
    BACK_RHOBTB1; BACK (BTB and C-terminal Kelch) domain found in Rho-related BTB domain-containing protein 1 (RhoBTB1)
  35. XM_047426100.1XP_047282056.1  rho-related BTB domain-containing protein 1 isoform X3

  36. XM_011540428.2XP_011538730.1  rho-related BTB domain-containing protein 1 isoform X4

    Conserved Domains (4) summary
    cd01873
    Location:13207
    RhoBTB; RhoBTB protein is an atypical member of the Rho family of small GTPases
    smart00174
    Location:17208
    RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
    smart00225
    Location:396455
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cl02518
    Location:406453
    BTB; BTB/POZ domain
  37. XM_047426103.1XP_047282059.1  rho-related BTB domain-containing protein 1 isoform X4

  38. XM_047426104.1XP_047282060.1  rho-related BTB domain-containing protein 1 isoform X4

  39. XM_047426105.1XP_047282061.1  rho-related BTB domain-containing protein 1 isoform X4

  40. XM_047426102.1XP_047282058.1  rho-related BTB domain-containing protein 1 isoform X4

RNA

  1. XR_007062022.1 RNA Sequence

  2. XR_007062020.1 RNA Sequence

  3. XR_007062021.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    61726193..61858729 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054367310.1XP_054223285.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  2. XM_054367326.1XP_054223301.1  rho-related BTB domain-containing protein 1 isoform X2

  3. XM_054367316.1XP_054223291.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  4. XM_054367303.1XP_054223278.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  5. XM_054367323.1XP_054223298.1  rho-related BTB domain-containing protein 1 isoform X2

  6. XM_054367307.1XP_054223282.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  7. XM_054367312.1XP_054223287.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  8. XM_054367324.1XP_054223299.1  rho-related BTB domain-containing protein 1 isoform X2

  9. XM_054367296.1XP_054223271.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  10. XM_054367300.1XP_054223275.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  11. XM_054367301.1XP_054223276.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  12. XM_054367302.1XP_054223277.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  13. XM_054367299.1XP_054223274.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  14. XM_054367314.1XP_054223289.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  15. XM_054367308.1XP_054223283.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  16. XM_054367329.1XP_054223304.1  rho-related BTB domain-containing protein 1 isoform X2

  17. XM_054367322.1XP_054223297.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  18. XM_054367313.1XP_054223288.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  19. XM_054367318.1XP_054223293.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  20. XM_054367297.1XP_054223272.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  21. XM_054367328.1XP_054223303.1  rho-related BTB domain-containing protein 1 isoform X2

  22. XM_054367319.1XP_054223294.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  23. XM_054367295.1XP_054223270.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  24. XM_054367311.1XP_054223286.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  25. XM_054367320.1XP_054223295.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  26. XM_054367306.1XP_054223281.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  27. XM_054367325.1XP_054223300.1  rho-related BTB domain-containing protein 1 isoform X2

  28. XM_054367321.1XP_054223296.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  29. XM_054367327.1XP_054223302.1  rho-related BTB domain-containing protein 1 isoform X2

  30. XM_054367315.1XP_054223290.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  31. XM_054367317.1XP_054223292.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  32. XM_054367309.1XP_054223284.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  33. XM_054367298.1XP_054223273.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  34. XM_054367304.1XP_054223279.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  35. XM_054367305.1XP_054223280.1  rho-related BTB domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    O94844
  36. XM_054367330.1XP_054223305.1  rho-related BTB domain-containing protein 1 isoform X3

  37. XM_054367331.1XP_054223306.1  rho-related BTB domain-containing protein 1 isoform X4

  38. XM_054367332.1XP_054223307.1  rho-related BTB domain-containing protein 1 isoform X4

  39. XM_054367334.1XP_054223309.1  rho-related BTB domain-containing protein 1 isoform X4

  40. XM_054367335.1XP_054223310.1  rho-related BTB domain-containing protein 1 isoform X4

  41. XM_054367333.1XP_054223308.1  rho-related BTB domain-containing protein 1 isoform X4

RNA

  1. XR_008488314.1 RNA Sequence

  2. XR_008488315.1 RNA Sequence

  3. XR_008488316.1 RNA Sequence