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ZBTB39 zinc finger and BTB domain containing 39 [ Homo sapiens (human) ]

Gene ID: 9880, updated on 23-Nov-2021

Summary

Official Symbol
ZBTB39provided by HGNC
Official Full Name
zinc finger and BTB domain containing 39provided by HGNC
Primary source
HGNC:HGNC:29014
See related
Ensembl:ENSG00000166860 MIM:619384
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF922
Expression
Broad expression in testis (RPKM 5.1), ovary (RPKM 2.2) and 25 other tissues See more
Orthologs
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Genomic context

See ZBTB39 in Genome Data Viewer
Location:
12q13.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (56998836..57006546, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (57392620..57400330, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr12.2240 Neighboring gene G protein-coupled receptor 182 Neighboring gene tachykinin precursor 3 Neighboring gene myosin IA

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: RDH16

Homology

Clone Names

  • KIAA0352

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 39

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014830.3NP_055645.1  zinc finger and BTB domain-containing protein 39

    See identical proteins and their annotated locations for NP_055645.1

    Status: VALIDATED

    Source sequence(s)
    AC026120, AK292468, BC152461
    Consensus CDS
    CCDS31839.1
    UniProtKB/Swiss-Prot
    O15060
    Related
    ENSP00000300101.2, ENST00000300101.3
    Conserved Domains (3) summary
    sd00017
    Location:607627
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:20119
    BTB; BTB/POZ domain
    pfam13465
    Location:619643
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    56998836..57006546 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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