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Rdh10 retinol dehydrogenase 10 (all-trans) [ Mus musculus (house mouse) ]

Gene ID: 98711, updated on 1-Nov-2022

Summary

Official Symbol
Rdh10provided by MGI
Official Full Name
retinol dehydrogenase 10 (all-trans)provided by MGI
Primary source
MGI:MGI:1924238
See related
Ensembl:ENSMUSG00000025921 AllianceGenome:MGI:1924238
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
m366Asp; D1Ertd762e; 3110069K09Rik; 4921506A21Rik
Summary
Enables NAD-retinol dehydrogenase activity. Acts upstream of or within several processes, including animal organ development; embryonic forelimb morphogenesis; and retinoic acid biosynthetic process. Located in membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human RDH10 (retinol dehydrogenase 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 15.9), duodenum adult (RPKM 10.2) and 28 other tissues See more
Orthologs
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Genomic context

See Rdh10 in Genome Data Viewer
Location:
1 A3; 1 4.94 cM
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (16176106..16202774)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (16105882..16132550)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930444P10 gene Neighboring gene ribosomal protein L7 Neighboring gene staufen double-stranded RNA binding protein 2 Neighboring gene RIKEN cDNA C130013N14 gene Neighboring gene predicted gene 7568

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables NAD-retinol dehydrogenase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables NAD-retinol dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables NADP-retinol dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within animal organ morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within bud elongation involved in lung branching IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within ear development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic camera-type eye development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic forelimb morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic organ development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic viscerocranium morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within metanephros development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neural crest cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within nose development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of retinoic acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within primary lung bud formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retinal metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within retinoic acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retinol metabolic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within visual perception ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
is_active_in lipid droplet IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
retinol dehydrogenase 10
NP_598593.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133832.3NP_598593.1  retinol dehydrogenase 10

    See identical proteins and their annotated locations for NP_598593.1

    Status: PROVISIONAL

    Source sequence(s)
    AC162442
    Consensus CDS
    CCDS14830.1
    UniProtKB/Swiss-Prot
    Q8CJ68, Q8VCH7
    Related
    ENSMUSP00000027053.8, ENSMUST00000027053.8
    Conserved Domains (2) summary
    cd05339
    Location:38307
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
    pfam00106
    Location:37252
    adh_short; short chain dehydrogenase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    16176106..16202774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)