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Fam8a1 family with sequence similarity 8, member A1 [ Mus musculus (house mouse) ]

Gene ID: 97863, updated on 30-Apr-2024

Summary

Official Symbol
Fam8a1provided by MGI
Official Full Name
family with sequence similarity 8, member A1provided by MGI
Primary source
MGI:MGI:2145496
See related
Ensembl:ENSMUSG00000069237 AllianceGenome:MGI:2145496
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be part of Hrd1p ubiquitin ligase complex. Orthologous to human FAM8A1 (family with sequence similarity 8 member A1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in duodenum adult (RPKM 22.1), CNS E18 (RPKM 20.6) and 28 other tissues See more
Orthologs
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Genomic context

See Fam8a1 in Genome Data Viewer
Location:
13 A5; 13 24.28 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (46822953..46831540)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (46669477..46678064)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34412 Neighboring gene RNA binding motif protein 24 Neighboring gene predicted gene, 35110 Neighboring gene STARR-seq mESC enhancer starr_34413 Neighboring gene STARR-seq mESC enhancer starr_34414 Neighboring gene cyclase associated actin cytoskeleton regulatory protein 2 Neighboring gene VISTA enhancer mm132 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:46712127-46712352 Neighboring gene STARR-seq mESC enhancer starr_34416 Neighboring gene STARR-seq mESC enhancer starr_34420 Neighboring gene nucleoporin 153 Neighboring gene STARR-positive B cell enhancer ABC_E9876 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:46831628-46831815 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:46831840-46832060 Neighboring gene predicted gene, 46412 Neighboring gene kinesin family member 13A Neighboring gene predicted gene, 24620

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of Hrd1p ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033192.3NP_001028364.1  protein FAM8A1 isoform 1

    See identical proteins and their annotated locations for NP_001028364.1

    Status: VALIDATED

    Source sequence(s)
    AC124598
    Consensus CDS
    CCDS26485.1
    UniProtKB/TrEMBL
    Q3TBV3, Q3URQ4
    Related
    ENSMUSP00000097144.4, ENSMUST00000099547.4
    Conserved Domains (1) summary
    pfam06271
    Location:230389
    RDD; RDD family
  2. NM_001377109.1NP_001364038.1  protein FAM8A1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC124598

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    46822953..46831540
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)