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RIMS3 regulating synaptic membrane exocytosis 3 [ Homo sapiens (human) ]

Gene ID: 9783, updated on 2-Mar-2021

Summary

Official Symbol
RIMS3provided by HGNC
Official Full Name
regulating synaptic membrane exocytosis 3provided by HGNC
Primary source
HGNC:HGNC:21292
See related
Ensembl:ENSG00000117016 MIM:611600
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NIM3; RIM3; RIM 3
Expression
Biased expression in brain (RPKM 26.0), adrenal (RPKM 4.0) and 9 other tissues See more
Orthologs
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Genomic context

See RIMS3 in Genome Data Viewer
Location:
1p34.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (40620680..40692104, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (41086352..41131354, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378673 Neighboring gene general transcription factor IIF subunit 2 pseudogene 2 Neighboring gene uncharacterized LOC105378675 Neighboring gene uncharacterized LOC105378674 Neighboring gene NFYC antisense RNA 1 Neighboring gene nuclear transcription factor Y subunit gamma Neighboring gene microRNA 30e Neighboring gene microRNA 30c-1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0237

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ion channel binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ion channel binding ISS
Inferred from Sequence or Structural Similarity
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
calcium ion-regulated exocytosis of neurotransmitter IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium-ion regulated exocytosis ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of membrane potential ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of synaptic plasticity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of synaptic vesicle exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of synaptic vesicle exocytosis ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoskeleton of presynaptic active zone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
presynaptic active zone TAS
Traceable Author Statement
more info
PubMed 
presynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
regulating synaptic membrane exocytosis protein 3
Names
RIM3 gamma
Rab-3 interacting molecule 3
rab-3-interacting molecule 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014747.3NP_055562.2  regulating synaptic membrane exocytosis protein 3

    See identical proteins and their annotated locations for NP_055562.2

    Status: VALIDATED

    Source sequence(s)
    AL031289
    Consensus CDS
    CCDS30687.1
    UniProtKB/Swiss-Prot
    Q9UJD0
    Related
    ENSP00000361769.3, ENST00000372684.8
    Conserved Domains (1) summary
    cl14603
    Location:141286
    C2; C2 domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    40620680..40692104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011542479.2XP_011540781.1  regulating synaptic membrane exocytosis protein 3 isoform X1

    Conserved Domains (1) summary
    cl14603
    Location:145290
    C2; C2 domain
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