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CD72 CD72 molecule [ Homo sapiens (human) ]

Gene ID: 971, updated on 22-Jan-2020

Summary

Official Symbol
CD72provided by HGNC
Official Full Name
CD72 moleculeprovided by HGNC
Primary source
HGNC:HGNC:1696
See related
Ensembl:ENSG00000137101 MIM:107272
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LYB2; CD72b
Expression
Biased expression in lymph node (RPKM 32.2), spleen (RPKM 30.4) and 4 other tissues See more
Orthologs

Genomic context

See CD72 in Genome Data Viewer
Location:
9p13.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (35609981..35618427, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (35609976..35618862, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein S29 pseudogene 17 Neighboring gene testis associated actin remodelling kinase 1 Neighboring gene microRNA 4667 Neighboring gene uncharacterized LOC101926948 Neighboring gene signaling threshold regulating transmembrane adaptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signaling receptor binding TAS
Traceable Author Statement
more info
PubMed 
transmembrane signaling receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
cell adhesion TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
B-cell differentiation antigen CD72
Names
CD72 antigen
lyb-2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001782.3NP_001773.1  B-cell differentiation antigen CD72

    See identical proteins and their annotated locations for NP_001773.1

    Status: VALIDATED

    Source sequence(s)
    AL357874, BC030227, M54992
    Consensus CDS
    CCDS6581.1
    UniProtKB/Swiss-Prot
    P21854
    UniProtKB/TrEMBL
    Q5TLG3
    Related
    ENSP00000259633.4, ENST00000259633.9
    Conserved Domains (2) summary
    smart00034
    Location:233351
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    TIGR04211
    Location:117219
    SH3_and_anchor; SH3 domain protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    35609981..35618427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006716893.2XP_006716956.1  B-cell differentiation antigen CD72 isoform X1

    Conserved Domains (2) summary
    pfam08826
    Location:168223
    DMPK_coil; DMPK coiled coil domain like
    smart00034
    Location:233319
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
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