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PHF14 PHD finger protein 14 [ Homo sapiens (human) ]

Gene ID: 9678, updated on 8-Jul-2021

Summary

Official Symbol
PHF14provided by HGNC
Official Full Name
PHD finger protein 14provided by HGNC
Primary source
HGNC:HGNC:22203
See related
Ensembl:ENSG00000106443
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in brain (RPKM 4.6), endometrium (RPKM 2.7) and 25 other tissues See more
Orthologs
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Genomic context

See PHF14 in Genome Data Viewer
Location:
7p21.3
Exon count:
19
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (10973872..11169618)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (11013499..11209245)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986767 Neighboring gene NDUFA4 mitochondrial complex associated Neighboring gene Sharpr-MPRA regulatory region 7861 Neighboring gene ribosomal protein L23a pseudogene 52 Neighboring gene uncharacterized LOC107986697 Neighboring gene uncharacterized LOC105375153 Neighboring gene nucleophosmin 1 pseudogene 11

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC176640

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in histone H3-K14 acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of MOZ/MORF histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007157.2NP_001007158.1  PHD finger protein 14 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AA699404, AA837024, AB018326, AK294419, BM834437
    Related
    ENSP00000489535.1, ENST00000634607.2
    Conserved Domains (4) summary
    cd15561
    Location:321377
    PHD1_PHF14; PHD finger 1 found in PHD finger protein 14 (PHF14) and similar proteins
    cd15562
    Location:727776
    PHD2_PHF14; PHD finger 2 found in PHD finger protein 14 (PHF14) and similar proteins
    cd15563
    Location:870918
    PHD3_PHF14; PHD finger 3 found in PHD finger protein 14 (PHF14) and similar proteins
    cd15674
    Location:385498
    ePHD_PHF14; Extended PHD finger found in PHD finger protein 14 (PHF14) and similar proteins
  2. NM_014660.4NP_055475.2  PHD finger protein 14 isoform 2

    See identical proteins and their annotated locations for NP_055475.2

    Status: VALIDATED

    Source sequence(s)
    AC005007, AK294419, BC152414, BM834437, DB359297
    Consensus CDS
    CCDS47542.1
    UniProtKB/Swiss-Prot
    O94880
    UniProtKB/TrEMBL
    B4DG57
    Related
    ENSP00000385795.3, ENST00000403050.7
    Conserved Domains (3) summary
    cd15561
    Location:321377
    PHD1_PHF14; PHD finger 1 found in PHD finger protein 14 (PHF14) and similar proteins
    cd15562
    Location:727776
    PHD2_PHF14; PHD finger 2 found in PHD finger protein 14 (PHF14) and similar proteins
    cd15674
    Location:385498
    ePHD_PHF14; Extended PHD finger found in PHD finger protein 14 (PHF14) and similar proteins

RNA

  1. NR_033435.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate internal exon, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC005007, AK294419, DB359297
    Related
    ENST00000642461.1
  2. NR_033436.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) has multiple differences, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK294419, AK295461, BG182843
    Related
    ENST00000423760.6

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    10973872..11169618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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