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PDE4DIP phosphodiesterase 4D interacting protein [ Homo sapiens (human) ]

Gene ID: 9659, updated on 11-Jun-2021

Summary

Official Symbol
PDE4DIPprovided by HGNC
Official Full Name
phosphodiesterase 4D interacting proteinprovided by HGNC
Primary source
HGNC:HGNC:15580
See related
Ensembl:ENSG00000178104 MIM:608117
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MMGL; CMYA2
Summary
The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Expression
Biased expression in heart (RPKM 86.3), brain (RPKM 18.4) and 10 other tissues See more
Orthologs
NEW
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Try the new Transcript table

Genomic context

See PDE4DIP in Genome Data Viewer
Location:
1q21.2
Exon count:
55
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (148808198..149051277)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (144851424..145076025, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene nudix hydrolase 4B Neighboring gene SEC22 homolog B3, pseudogene Neighboring gene uncharacterized LOC112268272 Neighboring gene RN7SK pseudogene 88 Neighboring gene RNA, U2 small nuclear 38, pseudogene Neighboring gene profilin-1-like Neighboring gene NBPF member 9 Neighboring gene uncharacterized LOC101929790

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Identification of novel germline polymorphisms governing capecitabine sensitivity.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC75440, DKFZp781J054

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables enzyme binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables molecular adaptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular protein-containing complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in regulation of Golgi organization IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in centrosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in myofibril ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
myomegalin
Names
cardiomyopathy-associated protein 2
myomegalin/phosphodiesterase 4D interacting protein variant 8

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_027693.2 RefSeqGene

    Range
    86277..229844
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001002810.4NP_001002810.1  myomegalin isoform 4

    See identical proteins and their annotated locations for NP_001002810.1

    Status: REVIEWED

    Source sequence(s)
    AC239802
    Consensus CDS
    CCDS72893.1
    UniProtKB/Swiss-Prot
    Q5VU43
    Related
    ENSP00000358353.4, ENST00000369347.8
    Conserved Domains (2) summary
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
    cl26527
    Location:39135
    ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
  2. NM_001002811.2NP_001002811.2  myomegalin isoform 5

    See identical proteins and their annotated locations for NP_001002811.2

    Status: REVIEWED

    Source sequence(s)
    AB007946, R42452
    Consensus CDS
    CCDS72894.1
    UniProtKB/Swiss-Prot
    Q5VU43
    Related
    ENSP00000316434.9, ENST00000313431.13
    Conserved Domains (2) summary
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    cl25732
    Location:4031095
    SMC_N; RecF/RecN/SMC N terminal domain
  3. NM_001002812.3NP_001002812.2  myomegalin isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC239802
    Consensus CDS
    CCDS72890.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A0A0MRL8
    Related
    ENSP00000358355.3, ENST00000369349.7
    Conserved Domains (3) summary
    TIGR02168
    Location:30679
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam07851
    Location:242337
    TMPIT; TMPIT-like protein
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
  4. NM_001195260.2NP_001182189.1  myomegalin isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC239802, BC025406, BI550399, CB529851, DA766011
    UniProtKB/Swiss-Prot
    Q5VU43
    Conserved Domains (2) summary
    PRK12704
    Location:2113
    PRK12704; phosphodiesterase; Provisional
    pfam07989
    Location:141
    Cnn_1N; Centrosomin N-terminal motif 1
  5. NM_001195261.2NP_001182190.1  myomegalin isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC239802, BC025406, BG776644, CB529851, DA766011
    Consensus CDS
    CCDS72889.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A087WYE4
    Related
    ENSP00000481731.1, ENST00000464103.5
    Conserved Domains (2) summary
    pfam07989
    Location:1376
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam16046
    Location:53118
    FAM76; FAM76 protein
  6. NM_001198832.3NP_001185761.2  myomegalin isoform 8

    Status: REVIEWED

    Source sequence(s)
    AA025132, AB007923, AC239802, AC245389, BC078660, DA816062
    Consensus CDS
    CCDS72888.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A087WVF8
    Related
    ENSP00000479409.1, ENST00000618462.4
    Conserved Domains (8) summary
    COG1196
    Location:4211206
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:20092056
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15191580
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:308403
    TMPIT; TMPIT-like protein
    pfam07989
    Location:72139
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:18231886
    SPICE; Centriole duplication and mitotic chromosome congression
    cl09111
    Location:116233
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  7. NM_001198834.4NP_001185763.3  myomegalin isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Consensus CDS
    CCDS72892.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A0A0MRM1
    Related
    ENSP00000358363.4, ENST00000369356.8
    Conserved Domains (7) summary
    TIGR02168
    Location:5679
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:21152162
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15631624
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:242337
    TMPIT; TMPIT-like protein
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:19291992
    SPICE; Centriole duplication and mitotic chromosome congression
    cl09111
    Location:50167
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  8. NM_001350520.1NP_001337449.1  myomegalin isoform 10

    Status: REVIEWED

    Source sequence(s)
    AA025132, AA434604, AB007923, AL598402, BC004860, BC078660, BI032558, BI033467, BQ673978, BQ719934, BX499615, CD300292, DA238288, DA328463, DA570225, DA719356, DA776112
    Conserved Domains (3) summary
    pfam06758
    Location:17181785
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    cl25732
    Location:4031237
    SMC_N; RecF/RecN/SMC N terminal domain
  9. NM_001350521.3NP_001337450.1  myomegalin isoform 11

    Status: REVIEWED

    Source sequence(s)
    AA025132, AA434604, AB007923, AC239802, AC245389, AL598402, BC078660, BX499615, DA238288, DA531671, DA900724
    Conserved Domains (2) summary
    pfam06758
    Location:16931760
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:140816
    SMC_N; RecF/RecN/SMC N terminal domain
  10. NM_001350522.2NP_001337451.1  myomegalin isoform 12

    Status: REVIEWED

    Source sequence(s)
    AA025132, AA434604, AB007923, AC239802, AC239804, AL598402, BC078660, BP360720, BX499615, DA238288, DA816062
    Conserved Domains (2) summary
    pfam06758
    Location:16221689
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:69745
    SMC_N; RecF/RecN/SMC N terminal domain
  11. NM_001350523.2NP_001337452.1  myomegalin isoform 13

    Status: REVIEWED

    Source sequence(s)
    AA025132, AB007923, AC239802, BC078660, BP360720, DA816062, DA900724
    Conserved Domains (2) summary
    pfam06758
    Location:15111578
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:69745
    SMC_N; RecF/RecN/SMC N terminal domain
  12. NM_001377392.1NP_001364321.1  myomegalin isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (5) summary
    COG0419
    Location:167767
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:19812203
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:3771175
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06758
    Location:16931760
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
  13. NM_001377393.1NP_001364322.1  myomegalin isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (5) summary
    COG0419
    Location:96696
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:18002022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:3061104
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06758
    Location:15121579
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07989
    Location:72139
    Cnn_1N; Centrosomin N-terminal motif 1
  14. NM_014644.6NP_055459.5  myomegalin isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Consensus CDS
    CCDS72891.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A0A0MRM0
    Related
    ENSP00000358360.3, ENST00000369354.7
    Conserved Domains (2) summary
    pfam06758
    Location:15561623
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:5679
    SMC_N; RecF/RecN/SMC N terminal domain
  15. NM_022359.7NP_071754.3  myomegalin isoform 3

    See identical proteins and their annotated locations for NP_071754.3

    Status: REVIEWED

    Source sequence(s)
    AB007923, AC239802, BI552090, CB048130, DA531671, F26249, HY309206
    Consensus CDS
    CCDS72887.1
    UniProtKB/Swiss-Prot
    Q5VU43
    Related
    ENSP00000482121.1, ENST00000530472.5
    Conserved Domains (2) summary
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
    cl09111
    Location:187304
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    148808198..149051277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011510172.2XP_011508474.1  myomegalin isoform X4

    Conserved Domains (8) summary
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:22522299
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:17001761
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:379474
    TMPIT; TMPIT-like protein
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:20662129
    SPICE; Centriole duplication and mitotic chromosome congression
    cl03951
    Location:307407
    CDC37_N; Cdc37 N terminal kinase binding
    cl09111
    Location:187304
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  2. XM_024451067.1XP_024306835.1  myomegalin isoform X22

    Conserved Domains (2) summary
    pfam06758
    Location:16931760
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:140816
    SMC_N; RecF/RecN/SMC N terminal domain
  3. XM_011510173.2XP_011508475.1  myomegalin isoform X5

    Conserved Domains (8) summary
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:22512298
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:16991760
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:379474
    TMPIT; TMPIT-like protein
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:20652128
    SPICE; Centriole duplication and mitotic chromosome congression
    cl03951
    Location:307407
    CDC37_N; Cdc37 N terminal kinase binding
    cl09111
    Location:187304
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  4. XM_011510175.2XP_011508477.1  myomegalin isoform X12

    UniProtKB/TrEMBL
    A0A075B749
    Related
    ENSP00000462316.2, ENST00000585156.5
    Conserved Domains (8) summary
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:22512298
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:16991760
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:379474
    TMPIT; TMPIT-like protein
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:20652128
    SPICE; Centriole duplication and mitotic chromosome congression
    cl03951
    Location:307407
    CDC37_N; Cdc37 N terminal kinase binding
    cl09111
    Location:187304
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  5. XM_011510176.2XP_011508478.1  myomegalin isoform X31

    Conserved Domains (8) summary
    COG1196
    Location:4921277
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:20802127
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15901651
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:379474
    TMPIT; TMPIT-like protein
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:18941957
    SPICE; Centriole duplication and mitotic chromosome congression
    cl09111
    Location:187304
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  6. XM_024451068.1XP_024306836.1  myomegalin isoform X30

    Conserved Domains (2) summary
    pfam06758
    Location:15821649
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:140816
    SMC_N; RecF/RecN/SMC N terminal domain
  7. XM_017002889.2XP_016858378.1  myomegalin isoform X25

  8. XM_017002894.2XP_016858383.1  myomegalin isoform X27

  9. XM_017002892.2XP_016858381.1  myomegalin isoform X27

  10. XM_017002887.1XP_016858376.1  myomegalin isoform X25

  11. XM_017002893.1XP_016858382.1  myomegalin isoform X27

  12. XM_017002888.1XP_016858377.1  myomegalin isoform X25

  13. XM_017002891.2XP_016858380.1  myomegalin isoform X27

  14. XM_006711646.2XP_006711709.1  myomegalin isoform X10

    Conserved Domains (8) summary
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:21812228
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:16291690
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:308403
    TMPIT; TMPIT-like protein
    pfam07989
    Location:72139
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:19952058
    SPICE; Centriole duplication and mitotic chromosome congression
    cl03951
    Location:236336
    CDC37_N; Cdc37 N terminal kinase binding
    cl09111
    Location:116233
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  15. XM_017002903.2XP_016858392.1  myomegalin isoform X35

  16. XM_006711650.4XP_006711713.1  myomegalin isoform X18

    Conserved Domains (8) summary
    TIGR02168
    Location:33682
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:21182165
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15661627
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:245340
    TMPIT; TMPIT-like protein
    pfam07989
    Location:1376
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:19321995
    SPICE; Centriole duplication and mitotic chromosome congression
    cl03951
    Location:173273
    CDC37_N; Cdc37 N terminal kinase binding
    cl09111
    Location:53170
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  17. XM_017002895.2XP_016858384.1  myomegalin isoform X27

  18. XM_006711651.1XP_006711714.1  myomegalin isoform X19

    Conserved Domains (8) summary
    TIGR02168
    Location:5679
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:21152162
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15631624
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:242337
    TMPIT; TMPIT-like protein
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:19291992
    SPICE; Centriole duplication and mitotic chromosome congression
    cl03951
    Location:170270
    CDC37_N; Cdc37 N terminal kinase binding
    cl09111
    Location:50167
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  19. XM_006711652.1XP_006711715.1  myomegalin isoform X21

    Conserved Domains (8) summary
    TIGR02168
    Location:5679
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:21142161
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15621623
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:242337
    TMPIT; TMPIT-like protein
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:19281991
    SPICE; Centriole duplication and mitotic chromosome congression
    cl03951
    Location:170270
    CDC37_N; Cdc37 N terminal kinase binding
    cl09111
    Location:50167
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  20. XM_011510179.1XP_011508481.1  myomegalin isoform X36

    Conserved Domains (8) summary
    TIGR02168
    Location:5679
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:21142161
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15621623
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:242337
    TMPIT; TMPIT-like protein
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:19281991
    SPICE; Centriole duplication and mitotic chromosome congression
    cl03951
    Location:170270
    CDC37_N; Cdc37 N terminal kinase binding
    cl09111
    Location:50167
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  21. XM_005277442.5XP_005277499.2  myomegalin isoform X3

  22. XM_017002876.2XP_016858365.1  myomegalin isoform X7

  23. XM_017002875.2XP_016858364.1  myomegalin isoform X6

  24. XM_006711642.3XP_006711705.1  myomegalin isoform X1

    Conserved Domains (7) summary
    COG1340
    Location:414714
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    TIGR02168
    Location:5181282
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:22782325
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:17261787
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam07851
    Location:405500
    TMPIT; TMPIT-like protein
    pfam15678
    Location:20922155
    SPICE; Centriole duplication and mitotic chromosome congression
  25. XM_005272981.4XP_005273038.2  myomegalin isoform X9

    Conserved Domains (7) summary
    COG1340
    Location:414714
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    TIGR02168
    Location:5181274
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:22782325
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:17261787
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam07851
    Location:405500
    TMPIT; TMPIT-like protein
    pfam15678
    Location:20922155
    SPICE; Centriole duplication and mitotic chromosome congression
  26. XM_017002884.2XP_016858373.1  myomegalin isoform X20

  27. XM_017002883.2XP_016858372.1  myomegalin isoform X17

  28. XM_011510174.2XP_011508476.1  myomegalin isoform X8

    Conserved Domains (7) summary
    COG1340
    Location:414714
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    TIGR02168
    Location:5181274
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:22162263
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:17261787
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam07851
    Location:405500
    TMPIT; TMPIT-like protein
    pfam15678
    Location:20302093
    SPICE; Centriole duplication and mitotic chromosome congression
  29. XM_017002881.2XP_016858370.1  myomegalin isoform X15

  30. XM_017002879.2XP_016858368.1  myomegalin isoform X14

  31. XM_017002896.2XP_016858385.1  myomegalin isoform X28

  32. XM_017002890.2XP_016858379.1  myomegalin isoform X26

  33. XM_006711643.3XP_006711706.1  myomegalin isoform X2

    Conserved Domains (7) summary
    COG1340
    Location:414714
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    TIGR02168
    Location:5181282
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:22772324
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:17251786
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam07851
    Location:405500
    TMPIT; TMPIT-like protein
    pfam15678
    Location:20912154
    SPICE; Centriole duplication and mitotic chromosome congression
  34. XM_017002882.2XP_016858371.1  myomegalin isoform X16

  35. XM_017002897.2XP_016858386.1  myomegalin isoform X29

  36. XM_006711648.3XP_006711711.1  myomegalin isoform X13

    Conserved Domains (8) summary
    COG0419
    Location:9901645
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1340
    Location:414714
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    TIGR02168
    Location:5181228
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:21682215
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:16161677
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam07851
    Location:405500
    TMPIT; TMPIT-like protein
    pfam15678
    Location:19822045
    SPICE; Centriole duplication and mitotic chromosome congression
  37. XM_017002885.2XP_016858374.1  myomegalin isoform X23

  38. XM_017002901.2XP_016858390.1  myomegalin isoform X34

  39. XM_017002900.2XP_016858389.1  myomegalin isoform X33

  40. XM_017002886.2XP_016858375.1  myomegalin isoform X24

RNA

  1. XR_001737551.2 RNA Sequence

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