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PDE4DIP phosphodiesterase 4D interacting protein [ Homo sapiens (human) ]

Gene ID: 9659, updated on 17-Sep-2022

Summary

Official Symbol
PDE4DIPprovided by HGNC
Official Full Name
phosphodiesterase 4D interacting proteinprovided by HGNC
Primary source
HGNC:HGNC:15580
See related
Ensembl:ENSG00000178104 MIM:608117; AllianceGenome:HGNC:15580
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MMGL; CMYA2
Summary
The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Expression
Biased expression in heart (RPKM 86.3), brain (RPKM 18.4) and 10 other tissues See more
Orthologs
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Genomic context

See PDE4DIP in Genome Data Viewer
Location:
1q21.2
Exon count:
56
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (148808434..149033016)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (145475230..145700086)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (144851427..145075933, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene nudix hydrolase 4B Neighboring gene SEC22 homolog B3, pseudogene Neighboring gene RN7SK pseudogene 88 Neighboring gene uncharacterized LOC112268272 Neighboring gene RNA, U2 small nuclear 38, pseudogene Neighboring gene profilin-1-like Neighboring gene NBPF member 9 Neighboring gene uncharacterized LOC101929790

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC75440, DKFZp781J054

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables enzyme binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables molecular adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables molecular adaptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in centrosome cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of microtubule nucleation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein-containing complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in regulation of Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of Golgi organization IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in centrosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in myofibril ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
myomegalin
Names
cardiomyopathy-associated protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_027693.2 RefSeqGene

    Range
    41253..229841
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001002810.5NP_001002810.1  myomegalin isoform 4

    See identical proteins and their annotated locations for NP_001002810.1

    Status: REVIEWED

    Source sequence(s)
    AC239802
    Consensus CDS
    CCDS72893.1
    UniProtKB/Swiss-Prot
    Q5VU43
    Related
    ENSP00000358353.4, ENST00000369347.8
    Conserved Domains (2) summary
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
    cl26527
    Location:39135
    ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
  2. NM_001002811.3NP_001002811.2  myomegalin isoform 5

    See identical proteins and their annotated locations for NP_001002811.2

    Status: REVIEWED

    Source sequence(s)
    AC239802
    Consensus CDS
    CCDS72894.1
    UniProtKB/Swiss-Prot
    Q5VU43
    Related
    ENSP00000316434.9, ENST00000313431.13
    Conserved Domains (2) summary
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    cl25732
    Location:4031095
    SMC_N; RecF/RecN/SMC N terminal domain
  3. NM_001002812.4NP_001002812.2  myomegalin isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC239802
    Consensus CDS
    CCDS72890.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A0A0MRL8
    Related
    ENSP00000358355.3, ENST00000369349.7
    Conserved Domains (3) summary
    TIGR02168
    Location:30679
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam07851
    Location:242337
    TMPIT; TMPIT-like protein
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
  4. NM_001195260.2NP_001182189.1  myomegalin isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC239802, BC025406, BI550399, CB529851, DA766011
    UniProtKB/Swiss-Prot
    Q5VU43
    Conserved Domains (2) summary
    PRK12704
    Location:2113
    PRK12704; phosphodiesterase; Provisional
    pfam07989
    Location:141
    Cnn_1N; Centrosomin N-terminal motif 1
  5. NM_001195261.2NP_001182190.1  myomegalin isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC239802, BC025406, BG776644, CB529851, DA766011
    Consensus CDS
    CCDS72889.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A087WYE4
    Related
    ENSP00000435920.1, ENST00000534536.5
    Conserved Domains (2) summary
    pfam07989
    Location:1376
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam16046
    Location:53118
    FAM76; FAM76 protein
  6. NM_001198832.4NP_001185761.2  myomegalin isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Consensus CDS
    CCDS72888.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A087WVF8
    Related
    ENSP00000479409.1, ENST00000618462.4
    Conserved Domains (8) summary
    COG1196
    Location:4211206
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:20092056
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15191580
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:308403
    TMPIT; TMPIT-like protein
    pfam07989
    Location:72139
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:18231886
    SPICE; Centriole duplication and mitotic chromosome congression
    cl09111
    Location:116233
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  7. NM_001198834.5NP_001185763.3  myomegalin isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Consensus CDS
    CCDS72892.1
    UniProtKB/Swiss-Prot
    Q5VU43
    UniProtKB/TrEMBL
    A0A0A0MRM1
    Related
    ENSP00000358363.4, ENST00000369356.8
    Conserved Domains (7) summary
    TIGR02168
    Location:5679
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:21152162
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15631624
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:242337
    TMPIT; TMPIT-like protein
    pfam07989
    Location:673
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:19291992
    SPICE; Centriole duplication and mitotic chromosome congression
    cl09111
    Location:50167
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  8. NM_001350520.2NP_001337449.1  myomegalin isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Conserved Domains (3) summary
    pfam06758
    Location:17181785
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    cl25732
    Location:4031237
    SMC_N; RecF/RecN/SMC N terminal domain
  9. NM_001350521.4NP_001337450.1  myomegalin isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    pfam06758
    Location:16931760
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:140816
    SMC_N; RecF/RecN/SMC N terminal domain
  10. NM_001350522.3NP_001337451.1  myomegalin isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    pfam06758
    Location:16221689
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:69745
    SMC_N; RecF/RecN/SMC N terminal domain
  11. NM_001350523.3NP_001337452.1  myomegalin isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    pfam06758
    Location:15111578
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:69745
    SMC_N; RecF/RecN/SMC N terminal domain
  12. NM_001377392.2NP_001364321.1  myomegalin isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Related
    ENSP00000512174.1, ENST00000695794.1
    Conserved Domains (5) summary
    COG0419
    Location:167767
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:19812203
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:3771175
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06758
    Location:16931760
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
  13. NM_001377393.2NP_001364322.1  myomegalin isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (5) summary
    COG0419
    Location:96696
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:18002022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:3061104
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06758
    Location:15121579
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07989
    Location:72139
    Cnn_1N; Centrosomin N-terminal motif 1
  14. NM_001395297.1NP_001382226.1  myomegalin isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Conserved Domains (2) summary
    COG1196
    Location:20072229
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:4031237
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  15. NM_001395298.1NP_001382227.1  myomegalin isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    UniProtKB/TrEMBL
    A0A075B749
    Related
    ENSP00000462316.2, ENST00000585156.5
    Conserved Domains (5) summary
    COG0419
    Location:167767
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:19802202
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:3771175
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06758
    Location:16921759
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
  16. NM_001395299.1NP_001382228.1  myomegalin isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Conserved Domains (2) summary
    COG1196
    Location:19442166
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:4031201
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  17. NM_001395300.1NP_001382229.1  myomegalin isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (3) summary
    COG0419
    Location:140730
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:19442166
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:3401138
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  18. NM_001395301.1NP_001382230.1  myomegalin isoform 20

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Conserved Domains (2) summary
    COG1196
    Location:20062175
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:4031201
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  19. NM_001395302.1NP_001382231.1  myomegalin isoform 21

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Related
    ENSP00000512160.1, ENST00000695768.1
    Conserved Domains (3) summary
    COG1196
    Location:19442113
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:150779
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:4951231
    SMC_N; RecF/RecN/SMC N terminal domain
  20. NM_001395303.1NP_001382232.1  myomegalin isoform 22

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:18702092
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  21. NM_001395304.1NP_001382233.1  myomegalin isoform 23

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:18482017
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  22. NM_001395305.1NP_001382234.1  myomegalin isoform 24

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:18482017
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  23. NM_001395306.1NP_001382235.1  myomegalin isoform 25

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:18002022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  24. NM_001395307.1NP_001382236.1  myomegalin isoform 26

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:18702055
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  25. NM_001395308.1NP_001382237.1  myomegalin isoform 27

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:18472032
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  26. NM_001395309.1NP_001382238.1  myomegalin isoform 28

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Conserved Domains (2) summary
    COG1196
    Location:17832005
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:4031247
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  27. NM_001395310.1NP_001382239.1  myomegalin isoform 29

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:18482033
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  28. NM_001395311.1NP_001382240.1  myomegalin isoform 30

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:17381907
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  29. NM_001395312.1NP_001382241.1  myomegalin isoform 31

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:4211336
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  30. NM_001395313.1NP_001382242.1  myomegalin isoform 32

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:18111996
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:79708
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  31. NM_001395314.1NP_001382243.1  myomegalin isoform 33

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Conserved Domains (2) summary
    COG1196
    Location:4211336
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  32. NM_001395315.1NP_001382244.1  myomegalin isoform 34

    Status: REVIEWED

    Source sequence(s)
    AC239802
    Related
    ENSP00000433392.1, ENST00000529945.2
    Conserved Domains (2) summary
    TIGR02168
    Location:4531095
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam18615
    Location:1376
    SMYLE_N; Short myomegalin-like EB1 binding proteins, N-terminal domain
  33. NM_001395316.1NP_001382245.1  myomegalin isoform 35

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (1) summary
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  34. NM_001395317.1NP_001382246.1  myomegalin isoform 36

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (2) summary
    PRK02224
    Location:6111088
    PRK02224; DNA double-strand break repair Rad50 ATPase
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  35. NM_001395318.1NP_001382247.1  myomegalin isoform 37

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (1) summary
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  36. NM_001395319.1NP_001382248.1  myomegalin isoform 38

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (1) summary
    TIGR02168
    Location:53729
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  37. NM_001395320.1NP_001382249.1  myomegalin isoform 39

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (1) summary
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  38. NM_001395321.1NP_001382250.1  myomegalin isoform 40

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (1) summary
    TIGR02168
    Location:79708
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  39. NM_001395322.1NP_001382251.1  myomegalin isoform 41

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (1) summary
    TIGR02168
    Location:18647
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  40. NM_001395323.1NP_001382252.1  myomegalin isoform 42

    Status: REVIEWED

    Source sequence(s)
    AC239802
    UniProtKB/TrEMBL
    E9PQG4
    Related
    ENSP00000436791.1, ENST00000479408.6
    Conserved Domains (2) summary
    TIGR02168
    Location:151466
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:28724
    SMC_N; RecF/RecN/SMC N terminal domain
  41. NM_001395324.1NP_001382253.1  myomegalin isoform 43

    Status: REVIEWED

    Source sequence(s)
    AC239802
    Conserved Domains (2) summary
    TIGR02168
    Location:151464
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam02463
    Location:28722
    SMC_N; RecF/RecN/SMC N terminal domain
  42. NM_001395325.1NP_001382254.1  myomegalin isoform 44

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Related
    ENSP00000512159.1, ENST00000695767.1
    Conserved Domains (1) summary
    COG1196
    Location:140342
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  43. NM_001395326.1NP_001382255.1  myomegalin isoform 45

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Related
    ENSP00000512161.1, ENST00000695769.1
    Conserved Domains (1) summary
    COG1196
    Location:67271
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  44. NM_001395327.1NP_001382256.1  myomegalin isoform 46

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (1) summary
    COG4942
    Location:57234
    EnvC; Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]
  45. NM_001395328.1NP_001382257.1  myomegalin isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
  46. NM_001395329.1NP_001382258.1  myomegalin isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Conserved Domains (2) summary
    PRK12704
    Location:2113
    PRK12704; phosphodiesterase; Provisional
    pfam07989
    Location:141
    Cnn_1N; Centrosomin N-terminal motif 1
  47. NM_001395426.1NP_001382355.1  myomegalin isoform 47

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804, AC245389
    Related
    ENSP00000512175.1, ENST00000695795.1
    Conserved Domains (2) summary
    COG1196
    Location:19102132
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:69745
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  48. NM_014644.7NP_055459.5  myomegalin isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC239804
    Consensus CDS
    CCDS72891.1
    UniProtKB/Swiss-Prot
    Q5VU43, Q9HCP5
    UniProtKB/TrEMBL
    A0A0A0MRM0
    Related
    ENSP00000358360.3, ENST00000369354.7
    Conserved Domains (2) summary
    pfam06758
    Location:15561623
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:5679
    SMC_N; RecF/RecN/SMC N terminal domain
  49. NM_022359.8NP_071754.3  myomegalin isoform 3

    See identical proteins and their annotated locations for NP_071754.3

    Status: REVIEWED

    Source sequence(s)
    AC239802, AC245389
    Consensus CDS
    CCDS72887.1
    UniProtKB/Swiss-Prot
    Q5VU43
    Related
    ENSP00000482121.1, ENST00000530472.5
    Conserved Domains (2) summary
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
    cl09111
    Location:187304
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    148808434..149033016
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047435065.1XP_047291021.1  myomegalin isoform X9

  2. XM_047435064.1XP_047291020.1  myomegalin isoform X8

  3. XM_047435063.1XP_047291019.1  myomegalin isoform X6

  4. XM_047435071.1XP_047291027.1  myomegalin isoform X17

  5. XM_047435070.1XP_047291026.1  myomegalin isoform X14

  6. XM_047435066.1XP_047291022.1  myomegalin isoform X12

  7. XM_011510176.3XP_011508478.1  myomegalin isoform X23

    Conserved Domains (8) summary
    COG1196
    Location:4921277
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:140816
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:20802127
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:15901651
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07851
    Location:379474
    TMPIT; TMPIT-like protein
    pfam07989
    Location:143210
    Cnn_1N; Centrosomin N-terminal motif 1
    pfam15678
    Location:18941957
    SPICE; Centriole duplication and mitotic chromosome congression
    cl09111
    Location:187304
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
  8. XM_047435075.1XP_047291031.1  myomegalin isoform X21

  9. XM_047435076.1XP_047291032.1  myomegalin isoform X24

  10. XM_024451068.2XP_024306836.1  myomegalin isoform X22

    Conserved Domains (2) summary
    pfam06758
    Location:15821649
    DUF1220; Repeat of unknown function (DUF1220)
    cl25732
    Location:140816
    SMC_N; RecF/RecN/SMC N terminal domain
  11. XM_047435082.1XP_047291038.1  myomegalin isoform X28

  12. XM_005272981.4XP_005273038.2  myomegalin isoform X1

    Conserved Domains (7) summary
    COG1340
    Location:414714
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    TIGR02168
    Location:5181274
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam05456
    Location:22782325
    eIF_4EBP; Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
    pfam06758
    Location:17261787
    DUF1220; Repeat of unknown function (DUF1220)
    pfam07776
    Location:474
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam07851
    Location:405500
    TMPIT; TMPIT-like protein
    pfam15678
    Location:20922155
    SPICE; Centriole duplication and mitotic chromosome congression
  13. XM_017002884.2XP_016858373.1  myomegalin isoform X7

  14. XM_017002883.2XP_016858372.1  myomegalin isoform X5

  15. XM_017002881.2XP_016858370.1  myomegalin isoform X3

  16. XM_017002879.2XP_016858368.1  myomegalin isoform X2

  17. XM_017002896.2XP_016858385.1  myomegalin isoform X15

  18. XM_017002890.2XP_016858379.1  myomegalin isoform X13

  19. XM_017002882.2XP_016858371.1  myomegalin isoform X4

  20. XM_017002897.2XP_016858386.1  myomegalin isoform X16

  21. XM_017002885.2XP_016858374.1  myomegalin isoform X10

  22. XM_047435073.1XP_047291029.1  myomegalin isoform X19

  23. XM_047435072.1XP_047291028.1  myomegalin isoform X18

  24. XM_017002901.2XP_016858390.1  myomegalin isoform X26

  25. XM_017002900.2XP_016858389.1  myomegalin isoform X25

  26. XM_017002886.2XP_016858375.1  myomegalin isoform X11

  27. XM_047435074.1XP_047291030.1  myomegalin isoform X20

  28. XM_047435081.1XP_047291037.1  myomegalin isoform X27

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    145475230..145700086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)