Format

Send to:

Choose Destination

MORF4L2 mortality factor 4 like 2 [ Homo sapiens (human) ]

Gene ID: 9643, updated on 7-Jun-2020

Summary

Official Symbol
MORF4L2provided by HGNC
Official Full Name
mortality factor 4 like 2provided by HGNC
Primary source
HGNC:HGNC:16849
See related
Ensembl:ENSG00000123562 MIM:300409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MRGX; MORFL2
Expression
Ubiquitous expression in ovary (RPKM 110.4), endometrium (RPKM 100.8) and 25 other tissues See more
Orthologs

Genomic context

See MORF4L2 in Genome Data Viewer
Location:
Xq22.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (103675498..103688158, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (102930426..102943086, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373302 Neighboring gene Sharpr-MPRA regulatory region 5968 Neighboring gene transcription elongation factor A like 1 Neighboring gene CNEP1R1 pseudogene 1 Neighboring gene MORF4L2 antisense RNA 1 Neighboring gene glycine receptor alpha 4 (pseudogene) Neighboring gene transmembrane protein 31 Neighboring gene uncharacterized LOC107985661

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0026

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
chromatin silencing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone H2A acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone H4 acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone deacetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of striated muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
regulation of growth IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
mortality factor 4-like protein 2
Names
MORF-related gene X protein
MSL3-2 protein
protein MSL3-2
transcription factor-like protein MRGX

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142418.1NP_001135890.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135890.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    BC093013, DA987770, DC419967
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  2. NM_001142419.1NP_001135891.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135891.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AL049610, BC093013, DA268606
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Related
    ENSP00000415476.2, ENST00000433176.6
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  3. NM_001142420.1NP_001135892.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135892.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AL049610, BC093013, DA268606
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  4. NM_001142421.1NP_001135893.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135893.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AL049610, BC093013, DA268606
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Related
    ENSP00000353643.1, ENST00000360458.5
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  5. NM_001142422.1NP_001135894.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135894.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AL049610, BC093013, DA268606
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  6. NM_001142423.1NP_001135895.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135895.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AL049610, BC093013, DA987770
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  7. NM_001142424.1NP_001135896.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135896.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    BC093013, DA987770
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  8. NM_001142425.1NP_001135897.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135897.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AL049610, BC093013, DA987770
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  9. NM_001142426.1NP_001135898.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135898.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AL049610, BC093013, DA987770
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Related
    ENSP00000410532.1, ENST00000451301.5
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  10. NM_001142427.1NP_001135899.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135899.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    BC093013, BM835303, DA268606
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  11. NM_001142428.1NP_001135900.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135900.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    BC093013, DA068448, DA268606
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  12. NM_001142429.1NP_001135901.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135901.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    BC093013, DA987770, DC301727
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  13. NM_001142430.1NP_001135902.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135902.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    BC093013, BM471743, DA987770
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  14. NM_001142431.1NP_001135903.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135903.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    BC093013, DA268606, DC366195
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  15. NM_001142432.1NP_001135904.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_001135904.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (16) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    BC093013, DA268606, DC424668
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG
  16. NM_012286.3NP_036418.1  mortality factor 4-like protein 2

    See identical proteins and their annotated locations for NP_036418.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1.
    Source sequence(s)
    AL049610, BC093013, DA987770
    Consensus CDS
    CCDS14512.1
    UniProtKB/Swiss-Prot
    Q15014
    Related
    ENSP00000391969.2, ENST00000441076.7
    Conserved Domains (1) summary
    pfam05712
    Location:102276
    MRG; MRG

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    103675498..103688158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center