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ARHGEF10 Rho guanine nucleotide exchange factor 10 [ Homo sapiens (human) ]

Gene ID: 9639, updated on 7-Sep-2023

Summary

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Official Symbol
ARHGEF10provided by HGNC
Official Full Name
Rho guanine nucleotide exchange factor 10provided by HGNC
Primary source
HGNC:HGNC:14103
See related
Ensembl:ENSG00000104728 MIM:608136; AllianceGenome:HGNC:14103
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SNCV; GEF10
Summary
This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Expression
Broad expression in testis (RPKM 15.4), lung (RPKM 12.1) and 22 other tissues See more
Orthologs
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Genomic context

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See ARHGEF10 in Genome Data Viewer
Location:
8p23.3
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (1823300..1958641)
RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (1601800..1736745)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (1772092..1906807)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377779 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1762347-1762848 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1762849-1763348 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1764028-1764696 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:1764697-1765364 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:1776960-1777876 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:1777877-1778792 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1781498-1781998 Neighboring gene microRNA 596 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:1783384-1783975 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1788613-1789492 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1789493-1790372 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1790373-1791250 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:1791725-1792924 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1813026-1813858 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1821545-1822256 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1829183-1829682 Neighboring gene Sharpr-MPRA regulatory region 1960 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr8:1854442-1855641 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:1859957-1860559 Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:1864189-1864688 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:1870370-1871569 Neighboring gene uncharacterized LOC100131395 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1897836-1898336 Neighboring gene KBTBD11 antisense RNA 1 Neighboring gene KBTBD11 overlapping transcript 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1926153-1926712 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:1926713-1927271 Neighboring gene kelch repeat and BTB domain containing 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. ARHGEF10 gene polymorphism is closely associated with the risk of ischemic stroke in Northern Han Chinese population. Li H, et al. Neurol Res, 2017 Feb. PMID 27934548
  2. Association of the Charcot-Marie-Tooth disease gene ARHGEF10 with paclitaxel induced peripheral neuropathy in NCCTG N08CA (Alliance). Boora GK, et al. J Neurol Sci, 2015 Oct 15. PMID 26143528, Free PMC Article
  3. The functional SNP rs4376531 in the ARHGEF gene is a risk factor for the atherothrombotic stroke in Han Chinese. Yin YY, et al. Neurol India, 2011 May-Jun. PMID 21743172
  4. Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10). Chaya T, et al. J Biol Chem, 2011 Aug 26. PMID 21719701, Free PMC Article
  5. Rho guanine nucleotide exchange factor ARHGEF10 is a putative tumor suppressor in pancreatic ductal adenocarcinoma. Joseph J, et al. Oncogene, 2020 Jan. PMID 31477830

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. this genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption
    Title: A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption.
  2. Treatment of ARHGEF10-depleted cells with the inhibitor dasatinib reduced levels of phospho Src kinase and attenuated motility and invasion in vitro. Together, our data indicate that ARHGEF10 may function as a tumor suppressor in Pancreatic ductal adenocarcinoma (PDAC).
    Title: Rho guanine nucleotide exchange factor ARHGEF10 is a putative tumor suppressor in pancreatic ductal adenocarcinoma.
  3. it was suggested that ARHGEF10 is involved in the regulation of Rab6A and Rab8A localization and invasion of breast carcinoma cells, in which Rab8 also acts via regulation of membrane trafficking.
    Title: Involvement of ARHGEF10, GEF for RhoA, in Rab6/Rab8-mediating membrane traffic.
  4. A single nucleotide polymorphisms (SNPs) associated with higher delta-6 desaturase (D6D) activity within the Rho guanine nucleotide exchange factor 10 (ARHGEF10) gene is potentially altering plasma triglyceride levels.
    Title: A common variant in ARHGEF10 alters delta-6 desaturase activity and influence susceptibility to hypertriglyceridemia.
  5. Ectopic expression of an N-terminal-truncated ARHGEF10 mutant led to the generation of large vesicle-like structures containing both Rab6 and Rab8.
    Title: ARHGEF10 directs the localization of Rab8 to Rab6-positive executive vesicles.
  6. This study provided new insights into the roles of ARHGEF10 SNPs rs2280887, rs9657362, and rs4480162 in the development and progression of ischemic stroke in northern Chinese Han population.
    Title: ARHGEF10 gene polymorphism is closely associated with the risk of ischemic stroke in Northern Han Chinese population.
  7. A significant association of ARHGEF10 with paclitaxel chemotherapy induced peripheral neuropathy was found.
    Title: Association of the Charcot-Marie-Tooth disease gene ARHGEF10 with paclitaxel induced peripheral neuropathy in NCCTG N08CA (Alliance).
  8. Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10).
    Title: Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10).
  9. the rs4376531 polymorphism in the ARHGEF10 gene is a risk factor for atherothrombotic stroke in the Han Chinese population
    Title: The functional SNP rs4376531 in the ARHGEF gene is a risk factor for the atherothrombotic stroke in Han Chinese.
  10. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Submit: New GeneRIF Correction See all GeneRIFs (15)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Autosomal dominant slowed nerve conduction velocity
MedGen: C1842357 OMIM: 608236 GeneReviews: Not available
Compare labs

EBI GWAS Catalog

Description
A genome-wide association study of brain lesion distribution in multiple sclerosis.
EBI GWAS Catalog
Genome-wide association study of selenium concentrations.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC131664, DKFZp686H0726

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity TAS
Traceable Author Statement
more info
  
enables kinesin binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in activation of GTPase activity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in centrosome duplication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in mitotic spindle assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in myelination in peripheral nervous system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of stress fiber assembly IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in positive regulation of stress fiber assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of small GTPase mediated signal transduction TAS
Traceable Author Statement
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 10
Names
Rho guanine nucleotide exchange factor (GEF) 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_008480.1 RefSeqGene

    Range
    5001..139659
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_234

mRNA and Protein(s)

  1. NM_001308152.2 → NP_001295081.1  rho guanine nucleotide exchange factor 10 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AA758332, AB002292, AC019257, BC112926
    Consensus CDS
    CCDS78297.1
    UniProtKB/Swiss-Prot
    O15013
    UniProtKB/TrEMBL
    A0A2X0U4L4
    Related
    ENSP00000427909.1, ENST00000520359.5
    Conserved Domains (2) summary
    pfam00621
    Location:366 → 544
    RhoGEF; RhoGEF domain
    cl17171
    Location:576 → 640
    PH-like; Pleckstrin homology-like domain

  2. NM_001308153.2 → NP_001295082.1  rho guanine nucleotide exchange factor 10 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, and contains an alternate exon in the 5' UTR and 5' coding region, which results in the use of an alternate start codon compared to variant 1. The encoded isoform (3) is longer and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AA758332, AB002292, AC019257, BC112926, CR749570
    Consensus CDS
    CCDS78296.1
    UniProtKB/Swiss-Prot
    O15013
    UniProtKB/TrEMBL
    A0A2X0U4L4
    Related
    ENSP00000431012.1, ENST00000518288.5
    Conserved Domains (2) summary
    pfam00621
    Location:429 → 606
    RhoGEF; RhoGEF domain
    cl17171
    Location:638 → 702
    PH-like; Pleckstrin homology-like domain

  3. NM_014629.4 → NP_055444.2  rho guanine nucleotide exchange factor 10 isoform 1

    See identical proteins and their annotated locations for NP_055444.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform (1).
    Source sequence(s)
    AA758332, AB002292, AC019257, AI348138, CN307765
    Consensus CDS
    CCDS34794.1
    UniProtKB/Swiss-Prot
    O15013
    UniProtKB/TrEMBL
    A0A2X0U4L4
    Related
    ENSP00000340297.3, ENST00000349830.8
    Conserved Domains (2) summary
    pfam00621
    Location:404 → 582
    RhoGEF; RhoGEF domain
    cl17171
    Location:614 → 678
    PH-like; Pleckstrin homology-like domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    1823300..1958641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047422457.1 → XP_047278413.1  rho guanine nucleotide exchange factor 10 isoform X10

    UniProtKB/TrEMBL
    A0A2X0U4L4

  2. XM_047422452.1 → XP_047278408.1  rho guanine nucleotide exchange factor 10 isoform X7

    UniProtKB/TrEMBL
    A0A2X0U4L4

  3. XM_047422450.1 → XP_047278406.1  rho guanine nucleotide exchange factor 10 isoform X4

    UniProtKB/TrEMBL
    A0A2X0U4L4

  4. XM_047422454.1 → XP_047278410.1  rho guanine nucleotide exchange factor 10 isoform X3

    UniProtKB/TrEMBL
    A0A2X0U4L4

  5. XM_047422456.1 → XP_047278412.1  rho guanine nucleotide exchange factor 10 isoform X9

    UniProtKB/TrEMBL
    A0A2X0U4L4

  6. XM_047422461.1 → XP_047278417.1  rho guanine nucleotide exchange factor 10 isoform X15

    UniProtKB/TrEMBL
    A0A2X0U4L4

  7. XM_005266041.5 → XP_005266098.1  rho guanine nucleotide exchange factor 10 isoform X4

    See identical proteins and their annotated locations for XP_005266098.1

    UniProtKB/TrEMBL
    A0A2X0U4L4
    Conserved Domains (3) summary
    cd00160
    Location:398 → 582
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    PTZ00441
    Location:3 → 250
    PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
    cl17171
    Location:615 → 679
    PH-like; Pleckstrin homology-like domain

  8. XM_047422459.1 → XP_047278415.1  rho guanine nucleotide exchange factor 10 isoform X12

    UniProtKB/TrEMBL
    A0A2X0U4L4

  9. XM_047422455.1 → XP_047278411.1  rho guanine nucleotide exchange factor 10 isoform X9

    UniProtKB/TrEMBL
    A0A2X0U4L4

  10. XM_047422458.1 → XP_047278414.1  rho guanine nucleotide exchange factor 10 isoform X11

    UniProtKB/TrEMBL
    A0A2X0U4L4

  11. XM_017014003.2 → XP_016869492.1  rho guanine nucleotide exchange factor 10 isoform X2

    UniProtKB/Swiss-Prot
    O14665, O15013, Q2KHR8, Q68D55, Q8IWD9, Q8IY77
    UniProtKB/TrEMBL
    A0A2X0U4L4
    Related
    ENSP00000381571.1, ENST00000398564.5
    Conserved Domains (2) summary
    pfam00621
    Location:429 → 607
    RhoGEF; RhoGEF domain
    cl17171
    Location:639 → 703
    PH-like; Pleckstrin homology-like domain

  12. XM_047422449.1 → XP_047278405.1  rho guanine nucleotide exchange factor 10 isoform X3

    UniProtKB/TrEMBL
    A0A2X0U4L4

  13. XM_024447335.2 → XP_024303103.1  rho guanine nucleotide exchange factor 10 isoform X1

    UniProtKB/TrEMBL
    A0A2X0U4L4
    Conserved Domains (3) summary
    cd00160
    Location:426 → 610
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    PTZ00441
    Location:27 → 278
    PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
    cl17171
    Location:643 → 707
    PH-like; Pleckstrin homology-like domain

  14. XM_047422453.1 → XP_047278409.1  rho guanine nucleotide exchange factor 10 isoform X8

    UniProtKB/TrEMBL
    A0A2X0U4L4

  15. XM_011534768.1 → XP_011533070.1  rho guanine nucleotide exchange factor 10 isoform X6

    See identical proteins and their annotated locations for XP_011533070.1

    UniProtKB/TrEMBL
    A0A2X0U4L4
    Conserved Domains (2) summary
    pfam00621
    Location:405 → 583
    RhoGEF; RhoGEF domain
    cl17171
    Location:615 → 679
    PH-like; Pleckstrin homology-like domain

  16. XM_047422451.1 → XP_047278407.1  rho guanine nucleotide exchange factor 10 isoform X5

    UniProtKB/TrEMBL
    A0A2X0U4L4

  17. XM_011534770.3 → XP_011533072.1  rho guanine nucleotide exchange factor 10 isoform X13

    See identical proteins and their annotated locations for XP_011533072.1

    UniProtKB/TrEMBL
    A0A2X0U4L4
    Conserved Domains (2) summary
    pfam00621
    Location:405 → 583
    RhoGEF; RhoGEF domain
    cl17171
    Location:615 → 679
    PH-like; Pleckstrin homology-like domain

  18. XM_047422460.1 → XP_047278416.1  rho guanine nucleotide exchange factor 10 isoform X14

    UniProtKB/TrEMBL
    A0A2X0U4L4

  19. XM_047422462.1 → XP_047278418.1  rho guanine nucleotide exchange factor 10 isoform X16

    UniProtKB/TrEMBL
    H0YAN8
    Related
    ENSP00000427768.1, ENST00000522435.5

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187576.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    6676..142017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054328834.1 → XP_054184809.1  rho guanine nucleotide exchange factor 10 isoform X10

    UniProtKB/TrEMBL
    A0A2X0U4L4

  2. XM_054328829.1 → XP_054184804.1  rho guanine nucleotide exchange factor 10 isoform X7

    UniProtKB/TrEMBL
    A0A2X0U4L4

  3. XM_054328826.1 → XP_054184801.1  rho guanine nucleotide exchange factor 10 isoform X4

    UniProtKB/TrEMBL
    A0A2X0U4L4

  4. XM_054328831.1 → XP_054184806.1  rho guanine nucleotide exchange factor 10 isoform X3

    UniProtKB/TrEMBL
    A0A2X0U4L4

  5. XM_054328833.1 → XP_054184808.1  rho guanine nucleotide exchange factor 10 isoform X9

    UniProtKB/TrEMBL
    A0A2X0U4L4

  6. XM_054328839.1 → XP_054184814.1  rho guanine nucleotide exchange factor 10 isoform X15

    UniProtKB/TrEMBL
    A0A2X0U4L4

  7. XM_054328825.1 → XP_054184800.1  rho guanine nucleotide exchange factor 10 isoform X4

    UniProtKB/TrEMBL
    A0A2X0U4L4

  8. XM_054328836.1 → XP_054184811.1  rho guanine nucleotide exchange factor 10 isoform X12

    UniProtKB/TrEMBL
    A0A2X0U4L4

  9. XM_054328832.1 → XP_054184807.1  rho guanine nucleotide exchange factor 10 isoform X9

    UniProtKB/TrEMBL
    A0A2X0U4L4

  10. XM_054328835.1 → XP_054184810.1  rho guanine nucleotide exchange factor 10 isoform X11

    UniProtKB/TrEMBL
    A0A2X0U4L4

  11. XM_054328823.1 → XP_054184798.1  rho guanine nucleotide exchange factor 10 isoform X2

    UniProtKB/Swiss-Prot
    O14665, O15013, Q2KHR8, Q68D55, Q8IWD9, Q8IY77
    UniProtKB/TrEMBL
    A0A2X0U4L4

  12. XM_054328824.1 → XP_054184799.1  rho guanine nucleotide exchange factor 10 isoform X3

    UniProtKB/TrEMBL
    A0A2X0U4L4

  13. XM_054328822.1 → XP_054184797.1  rho guanine nucleotide exchange factor 10 isoform X1

    UniProtKB/TrEMBL
    A0A2X0U4L4

  14. XM_054328830.1 → XP_054184805.1  rho guanine nucleotide exchange factor 10 isoform X8

    UniProtKB/TrEMBL
    A0A2X0U4L4

  15. XM_054328828.1 → XP_054184803.1  rho guanine nucleotide exchange factor 10 isoform X6

    UniProtKB/TrEMBL
    A0A2X0U4L4

  16. XM_054328827.1 → XP_054184802.1  rho guanine nucleotide exchange factor 10 isoform X5

    UniProtKB/TrEMBL
    A0A2X0U4L4

  17. XM_054328837.1 → XP_054184812.1  rho guanine nucleotide exchange factor 10 isoform X13

    UniProtKB/TrEMBL
    A0A2X0U4L4

  18. XM_054328838.1 → XP_054184813.1  rho guanine nucleotide exchange factor 10 isoform X14

    UniProtKB/TrEMBL
    A0A2X0U4L4

  19. XM_054328840.1 → XP_054184815.1  rho guanine nucleotide exchange factor 10 isoform X16

    UniProtKB/TrEMBL
    H0YAN8

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    1601800..1736745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054361550.1 → XP_054217525.1  rho guanine nucleotide exchange factor 10 isoform X10

    UniProtKB/TrEMBL
    A0A2X0U4L4

  2. XM_054361545.1 → XP_054217520.1  rho guanine nucleotide exchange factor 10 isoform X7

    UniProtKB/TrEMBL
    A0A2X0U4L4

  3. XM_054361542.1 → XP_054217517.1  rho guanine nucleotide exchange factor 10 isoform X4

    UniProtKB/TrEMBL
    A0A2X0U4L4

  4. XM_054361547.1 → XP_054217522.1  rho guanine nucleotide exchange factor 10 isoform X3

    UniProtKB/TrEMBL
    A0A2X0U4L4

  5. XM_054361549.1 → XP_054217524.1  rho guanine nucleotide exchange factor 10 isoform X9

    UniProtKB/TrEMBL
    A0A2X0U4L4

  6. XM_054361555.1 → XP_054217530.1  rho guanine nucleotide exchange factor 10 isoform X15

    UniProtKB/TrEMBL
    A0A2X0U4L4

  7. XM_054361541.1 → XP_054217516.1  rho guanine nucleotide exchange factor 10 isoform X4

    UniProtKB/TrEMBL
    A0A2X0U4L4

  8. XM_054361552.1 → XP_054217527.1  rho guanine nucleotide exchange factor 10 isoform X12

    UniProtKB/TrEMBL
    A0A2X0U4L4

  9. XM_054361548.1 → XP_054217523.1  rho guanine nucleotide exchange factor 10 isoform X9

    UniProtKB/TrEMBL
    A0A2X0U4L4

  10. XM_054361551.1 → XP_054217526.1  rho guanine nucleotide exchange factor 10 isoform X11

    UniProtKB/TrEMBL
    A0A2X0U4L4

  11. XM_054361539.1 → XP_054217514.1  rho guanine nucleotide exchange factor 10 isoform X2

    UniProtKB/Swiss-Prot
    O14665, O15013, Q2KHR8, Q68D55, Q8IWD9, Q8IY77
    UniProtKB/TrEMBL
    A0A2X0U4L4

  12. XM_054361540.1 → XP_054217515.1  rho guanine nucleotide exchange factor 10 isoform X3

    UniProtKB/TrEMBL
    A0A2X0U4L4

  13. XM_054361538.1 → XP_054217513.1  rho guanine nucleotide exchange factor 10 isoform X1

    UniProtKB/TrEMBL
    A0A2X0U4L4

  14. XM_054361546.1 → XP_054217521.1  rho guanine nucleotide exchange factor 10 isoform X8

    UniProtKB/TrEMBL
    A0A2X0U4L4

  15. XM_054361544.1 → XP_054217519.1  rho guanine nucleotide exchange factor 10 isoform X6

    UniProtKB/TrEMBL
    A0A2X0U4L4

  16. XM_054361543.1 → XP_054217518.1  rho guanine nucleotide exchange factor 10 isoform X5

    UniProtKB/TrEMBL
    A0A2X0U4L4

  17. XM_054361553.1 → XP_054217528.1  rho guanine nucleotide exchange factor 10 isoform X13

    UniProtKB/TrEMBL
    A0A2X0U4L4

  18. XM_054361554.1 → XP_054217529.1  rho guanine nucleotide exchange factor 10 isoform X14

    UniProtKB/TrEMBL
    A0A2X0U4L4

  19. XM_054361556.1 → XP_054217531.1  rho guanine nucleotide exchange factor 10 isoform X16

    UniProtKB/TrEMBL
    H0YAN8

RNA

  1. XR_008487897.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O15013.4 GenPept UniProtKB/Swiss-Prot:O15013

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