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VPS9D1 VPS9 domain containing 1 [ Homo sapiens (human) ]

Gene ID: 9605, updated on 25-Jan-2022

Summary

Official Symbol
VPS9D1provided by HGNC
Official Full Name
VPS9 domain containing 1provided by HGNC
Primary source
HGNC:HGNC:13526
See related
Ensembl:ENSG00000075399 MIM:619292; AllianceGenome:HGNC:13526
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATPBL; ATP-BL; C16orf7
Summary
Enables identical protein binding activity. Predicted to be involved in ATP synthesis coupled proton transport. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in brain (RPKM 5.5), appendix (RPKM 5.3) and 25 other tissues See more
Orthologs
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Genomic context

See VPS9D1 in Genome Data Viewer
Location:
16q24.3
Exon count:
18
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (89707133..89721231, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (89773542..89787306, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 10 Neighboring gene spermatogenesis associated 2 like Neighboring gene VPS9D1 antisense RNA 1 Neighboring gene zinc finger protein 276 Neighboring gene FA complementation group A Neighboring gene Sharpr-MPRA regulatory region 3988 Neighboring gene uncharacterized LOC107984817 Neighboring gene spire type actin nucleation factor 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transporter activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in ATP synthesis coupled proton transport TAS
Traceable Author Statement
more info
PubMed 
involved_in regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in endocytic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
VPS9 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004913.3NP_004904.2  VPS9 domain-containing protein 1

    See identical proteins and their annotated locations for NP_004904.2

    Status: VALIDATED

    Source sequence(s)
    AB018551, AC010538, AI458261, BC052626, BM920493, BY795348, CA428853
    Consensus CDS
    CCDS42220.1
    UniProtKB/Swiss-Prot
    Q9Y2B5
    Related
    ENSP00000374037.3, ENST00000389386.8
    Conserved Domains (1) summary
    pfam02204
    Location:509624
    VPS9; Vacuolar sorting protein 9 (VPS9) domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    89707133..89721231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006721350.3XP_006721413.1  VPS9 domain-containing protein 1 isoform X5

    Conserved Domains (1) summary
    cl19569
    Location:510590
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
  2. XM_005256329.5XP_005256386.1  VPS9 domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    pfam02204
    Location:510625
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
  3. XM_011523476.3XP_011521778.1  VPS9 domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    pfam02204
    Location:509624
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
  4. XM_005256330.4XP_005256387.1  VPS9 domain-containing protein 1 isoform X7

    See identical proteins and their annotated locations for XP_005256387.1

    Conserved Domains (1) summary
    pfam02204
    Location:440555
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
  5. XM_011523480.3XP_011521782.1  VPS9 domain-containing protein 1 isoform X7

    See identical proteins and their annotated locations for XP_011521782.1

    Related
    ENSP00000454244.1, ENST00000561976.5
    Conserved Domains (1) summary
    pfam02204
    Location:440555
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
  6. XM_011523478.3XP_011521780.1  VPS9 domain-containing protein 1 isoform X4

    Conserved Domains (1) summary
    pfam02204
    Location:475590
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
  7. XM_011523477.3XP_011521779.1  VPS9 domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    pfam02204
    Location:476591
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
  8. XM_005256331.2XP_005256388.1  VPS9 domain-containing protein 1 isoform X8

    Conserved Domains (1) summary
    pfam02204
    Location:344459
    VPS9; Vacuolar sorting protein 9 (VPS9) domain
  9. XM_011523479.3XP_011521781.1  VPS9 domain-containing protein 1 isoform X6

    Conserved Domains (1) summary
    COG4717
    Location:122244
    YhaN; Uncharacterized protein YhaN, contains AAA domain [Function unknown]

RNA

  1. XR_933495.3 RNA Sequence

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