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IER2 immediate early response 2 [ Homo sapiens (human) ]

Gene ID: 9592, updated on 12-Oct-2019

Summary

Official Symbol
IER2provided by HGNC
Official Full Name
immediate early response 2provided by HGNC
Primary source
HGNC:HGNC:28871
See related
Ensembl:ENSG00000160888
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ETR101
Expression
Ubiquitous expression in prostate (RPKM 98.0), bone marrow (RPKM 95.1) and 24 other tissues See more
Orthologs

Genomic context

See IER2 in Genome Data Viewer
Location:
19p13.13
Exon count:
2
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (13150411..13154911)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (13261282..13265722)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase 1 Neighboring gene nucleus accumbens associated 1 Neighboring gene syntaxin 10 Neighboring gene ribosomal protein L12 pseudogene 42 Neighboring gene Sharpr-MPRA regulatory region 13602

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC15265, MGC111472

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
response to fibroblast growth factor ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
immediate early response gene 2 protein
Names
chxI protein homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004907.3NP_004898.2  immediate early response gene 2 protein

    See identical proteins and their annotated locations for NP_004898.2

    Status: VALIDATED

    Source sequence(s)
    AC011446, BC072432
    Consensus CDS
    CCDS12295.1
    UniProtKB/Swiss-Prot
    Q9BTL4
    UniProtKB/TrEMBL
    A0A024R7H1
    Related
    ENSP00000292433.2, ENST00000292433.4
    Conserved Domains (1) summary
    pfam05760
    Location:1113
    IER; Immediate early response protein (IER)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    13150411..13154911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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