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SPAG7 sperm associated antigen 7 [ Homo sapiens (human) ]

Gene ID: 9552, updated on 10-Oct-2020

Summary

Official Symbol
SPAG7provided by HGNC
Official Full Name
sperm associated antigen 7provided by HGNC
Primary source
HGNC:HGNC:11216
See related
Ensembl:ENSG00000091640 MIM:610056
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ACRP; FSA-1
Expression
Ubiquitous expression in heart (RPKM 25.7), kidney (RPKM 18.4) and 25 other tissues See more
Orthologs

Genomic context

See SPAG7 in Genome Data Viewer
Location:
17p13.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (4959226..4967817, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (4862521..4871132, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene profilin 1 Neighboring gene enolase 3 Neighboring gene calmodulin binding transcription activator 2 Neighboring gene microRNA 6864 Neighboring gene microRNA 6865

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC20134

Gene Ontology Provided by GOA

Function Evidence Code Pubs
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004890.3NP_004881.2  sperm-associated antigen 7

    See identical proteins and their annotated locations for NP_004881.2

    Status: VALIDATED

    Source sequence(s)
    BC011934, BP308951
    Consensus CDS
    CCDS42240.1
    UniProtKB/Swiss-Prot
    O75391
    Related
    ENSP00000206020.3, ENST00000206020.8
    Conserved Domains (2) summary
    cd02636
    Location:49109
    R3H_sperm-antigen; R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted ...
    cl19818
    Location:176
    DUF106; Integral membrane protein DUF106

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    4959226..4967817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006721600.2XP_006721663.1  sperm-associated antigen 7 isoform X1

    See identical proteins and their annotated locations for XP_006721663.1

    UniProtKB/TrEMBL
    I3L0X5
    Related
    ENSP00000458405.1, ENST00000573366.5
    Conserved Domains (1) summary
    cd02636
    Location:158
    R3H_sperm-antigen; R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted ...
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