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IGDCC3 immunoglobulin superfamily DCC subclass member 3 [ Homo sapiens (human) ]

Gene ID: 9543, updated on 13-Mar-2020

Summary

Official Symbol
IGDCC3provided by HGNC
Official Full Name
immunoglobulin superfamily DCC subclass member 3provided by HGNC
Primary source
HGNC:HGNC:9700
See related
Ensembl:ENSG00000174498 MIM:604184
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PUNC; HsT18880
Expression
Biased expression in placenta (RPKM 4.0), testis (RPKM 2.0) and 4 other tissues See more
Orthologs

Genomic context

See IGDCC3 in Genome Data Viewer
Location:
15q22.31
Exon count:
16
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (65327127..65378002, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (65619465..65670378, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene RNA, U5A small nuclear 1 Neighboring gene RNA, U5B small nuclear 1 Neighboring gene immunoglobulin superfamily DCC subclass member 4 Neighboring gene dipeptidyl peptidase 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
neuromuscular process controlling balance IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
immunoglobulin superfamily DCC subclass member 3
Names
putative neuronal cell adhesion molecule

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_004884.4NP_004875.2  immunoglobulin superfamily DCC subclass member 3 precursor

    See identical proteins and their annotated locations for NP_004875.2

    Status: VALIDATED

    Source sequence(s)
    AC105129, AI740721, BC067107
    Consensus CDS
    CCDS10205.1
    UniProtKB/Swiss-Prot
    Q8IVU1
    Related
    ENSP00000332773.4, ENST00000327987.9
    Conserved Domains (6) summary
    cd00096
    Location:347414
    Ig; Immunoglobulin domain
    smart00410
    Location:244326
    IG_like; Immunoglobulin like
    cd00063
    Location:424517
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:331417
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:522603
    fn3; Fibronectin type III domain
    cl11960
    Location:44135
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    65327127..65378002 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011522241.2XP_011520543.2  immunoglobulin superfamily DCC subclass member 3 isoform X3

    Conserved Domains (5) summary
    cd00063
    Location:328421
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:235321
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:426507
    fn3; Fibronectin type III domain
    pfam13927
    Location:142214
    Ig_3; Immunoglobulin domain
    cl11960
    Location:47131
    Ig; Immunoglobulin domain
  2. XM_011522244.1XP_011520546.1  immunoglobulin superfamily DCC subclass member 3 isoform X2

    Conserved Domains (6) summary
    cd00096
    Location:210277
    Ig; Immunoglobulin domain
    smart00410
    Location:107189
    IG_like; Immunoglobulin like
    cd00063
    Location:287380
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:194280
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:385466
    fn3; Fibronectin type III domain
    cl11960
    Location:690
    Ig; Immunoglobulin domain
  3. XM_011522243.1XP_011520545.1  immunoglobulin superfamily DCC subclass member 3 isoform X1

    Conserved Domains (6) summary
    cd00096
    Location:224291
    Ig; Immunoglobulin domain
    smart00410
    Location:121203
    IG_like; Immunoglobulin like
    cd00063
    Location:301394
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:208294
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:399480
    fn3; Fibronectin type III domain
    cl11960
    Location:20104
    Ig; Immunoglobulin domain
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