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SLC4A7 solute carrier family 4 member 7 [ Homo sapiens (human) ]

Gene ID: 9497, updated on 6-Jan-2026
Official Symbol
SLC4A7provided by HGNC
Official Full Name
solute carrier family 4 member 7provided by HGNC
Primary source
HGNC:HGNC:11033
See related
Ensembl:ENSG00000033867 MIM:603353; AllianceGenome:HGNC:11033
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NBC2; NBC3; SBC2; NBCN1; SLC4A6
Summary
This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Expression
Ubiquitous expression in duodenum (RPKM 27.5), small intestine (RPKM 8.8) and 20 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See SLC4A7 in Genome Data Viewer
Location:
3p24.1
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (27372723..27484384, complement)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (27374872..27486481, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (27414214..27525875, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene NIMA related kinase 10 Neighboring gene MICOS10 pseudogene 3 Neighboring gene MPRA-validated peak4579 silencer Neighboring gene RNA, U6 small nuclear 342, pseudogene Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr3:27352339-27353538 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:27410132-27410632 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:27483819-27484320 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:27505552-27506411 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:27513115-27513615 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19616 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19617 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19618 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:27525149-27525925 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19619 Neighboring gene ribosomal protein S20 pseudogene 15 Neighboring gene uncharacterized LOC105377005 Neighboring gene ubiquitin A-52 residue ribosomal protein fusion product 1 pseudogene 4 Neighboring gene RNA, U1 small nuclear 96, pseudogene

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Molecular cloning of a new sodium bicarbonate cotransporter cDNA from human retina. Ishibashi K, et al. Biochem Biophys Res Commun, 1998 May 19. PMID 9610397
  2. Mapping of the human NBC3 (SLC4A7) gene to chromosome 3p22. Pushkin A, et al. Genomics, 1999 Apr 15. PMID 10198178
  3. Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family. Pushkin A, et al. J Biol Chem, 1999 Jun 4. PMID 10347222
  4. The Hypertension Risk Variant Rs820430 Functions as an Enhancer of SLC4A7. Wang L, et al. Am J Hypertens, 2017 Feb. PMID 27784683
  5. Alternative transcription of sodium/bicarbonate transporter SLC4A7 gene enhanced by single nucleotide polymorphisms. Park HJ, et al. Physiol Genomics, 2017 Mar 1. PMID 28087757, Free PMC Article

See all (115) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Antibodies toward Na[+],HCO3[-]-cotransporter NBCn1/SLC4A7 block net acid extrusion and cause pH-dependent growth inhibition and apoptosis in breast cancer.
    Title: Antibodies toward Na(+),HCO(3)(-)-cotransporter NBCn1/SLC4A7 block net acid extrusion and cause pH-dependent growth inhibition and apoptosis in breast cancer.
  2. Update on the relationship between the SLC4A7 variant rs4973768 and breast cancer risk: a systematic review and meta-analysis.
    Title: Update on the relationship between the SLC4A7 variant rs4973768 and breast cancer risk: a systematic review and meta-analysis.
  3. Dynamic localization of the Na+-HCO3- co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia.
    Title: Dynamic localization of the Na+-HCO3- co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia.
  4. The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis.
    Title: The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis.
  5. Increased Alcohol Consumption in Mice Lacking Sodium Bicarbonate Transporter NBCn1.
    Title: Increased Alcohol Consumption in Mice Lacking Sodium Bicarbonate Transporter NBCn1.
  6. SLC4A7 and bicarbonate-driven cytoplasmic pH homeostasis as an important element of phagocytosis and the associated microbicidal functions in macrophages.
    Title: The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification.
  7. rs3278 and rs3755652 stimulate an alternative transcription of the SLC4A7 gene, increasing the production of a defective transporter.
    Title: Alternative transcription of sodium/bicarbonate transporter SLC4A7 gene enhanced by single nucleotide polymorphisms.
  8. the disease-associated T allele of a new hypertension risk variant rs820430 linked increased hypertension risk through higher SLC4A7 expression, and rs820430 functioned as an enhancer of SLC4A7 transcription by allele distinctively increased c-Fos transcription factor binding.
    Title: The Hypertension Risk Variant Rs820430 Functions as an Enhancer of SLC4A7.
  9. this is the first work to demonstrate 3'UTR-mediated NBCn1 regulation, shows that p95HER2 regulates NBCn1 expression at multiple levels, and substantiates the central position of p95HER2-NBCn1 signaling in breast cancer.
    Title: Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes.
  10. The finding of a genotypic influence on SLC4A7 expression and pHi regulation in vascular smooth muscle cells provides an insight into the molecular mechanism underlying the association of variation at the SLC4A7 locus with blood pressure
    Title: Increased NBCn1 expression, Na+/HCO3- co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension.
Submit: New GeneRIF Correction See all GeneRIFs (25)

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.
EBI GWAS Catalog
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
EBI GWAS Catalog
Genome-wide association study identifies five new breast cancer susceptibility loci.
EBI GWAS Catalog
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
EBI GWAS Catalog
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
EBI GWAS Catalog
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
EBI GWAS Catalog
Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.
EBI GWAS Catalog

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Replication interactions

Interaction Pubs
HIV-1 infection (VSV-G pseudotyped) of CEMT4 T cells downregulates plasma membrane expression of SLC4A7 PubMed
Knockdown of solute carrier family 4, sodium bicarbonate cotransporter, member 7 (SLC4A7) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp686H168

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables monoatomic anion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sodium:bicarbonate symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sodium:bicarbonate symporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables sodium:bicarbonate symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables sodium:bicarbonate symporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables sodium:bicarbonate symporter activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables sodium:bicarbonate symporter activity TAS
Traceable Author Statement
more info
  
enables solute:inorganic anion antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in auditory receptor cell development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in bicarbonate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in bicarbonate transport IEA
Inferred from Electronic Annotation
more info
  
involved_in bicarbonate transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in bicarbonate transport TAS
Traceable Author Statement
more info
  
involved_in cellular response to growth factor stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in monoatomic anion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic anion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in phagosome acidification IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in purine nucleotide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pyrimidine nucleotide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of intracellular pH IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
  
located_in stereocilium IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
sodium bicarbonate cotransporter 3
Names
bicarbonate transporter
electroneutral Na/HCO(3) cotransporter
sodium bicarbonate cotransporter 2
sodium bicarbonate cotransporter 2b
solute carrier family 4, sodium bicarbonate cotransporter, member 7

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_032673.1 RefSeqGene

    Range
    5037..116698
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258379.2 → NP_001245308.1  sodium bicarbonate cotransporter 3 isoform b

    See identical proteins and their annotated locations for NP_001245308.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. This variant has additional differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.
    Source sequence(s)
    AA569234, AK310865, AL389947, CR627428, DA756057, EU499349, EU934246
    Consensus CDS
    CCDS58820.1
    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000407382.1, ENST00000455077.5
    Conserved Domains (1) summary
    cl26877
    Location:118 → 1016
    Band_3_cyto; Band 3 cytoplasmic domain

  2. NM_001258380.2 → NP_001245309.1  sodium bicarbonate cotransporter 3 isoform c

    See identical proteins and their annotated locations for NP_001245309.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform c), compared to isoform a.
    Source sequence(s)
    AA569234, AC099535, AF089726, AK310865, AL389947, EU934250
    Consensus CDS
    CCDS58819.1
    UniProtKB/TrEMBL
    C9JRP1
    Related
    ENSP00000416368.1, ENST00000428386.5
    Conserved Domains (3) summary
    TIGR00834
    Location:113 → 1011
    ae; anion exchange protein
    pfam00955
    Location:451 → 964
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:141 → 408
    Band_3_cyto; Band 3 cytoplasmic domain

  3. NM_001321103.2 → NP_001308032.1  sodium bicarbonate cotransporter 3 isoform d

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, EU499349, EU934248, EU934249, FJ178574
    Consensus CDS
    CCDS82747.1
    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000390394.1, ENST00000454389.6
    Conserved Domains (3) summary
    TIGR00834
    Location:122 → 1144
    ae; anion exchange protein
    pfam00955
    Location:584 → 1097
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:150 → 541
    Band_3_cyto; Band 3 cytoplasmic domain

  4. NM_001321104.2 → NP_001308033.1  sodium bicarbonate cotransporter 3 isoform e

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, EU934250
    Consensus CDS
    CCDS82749.1
    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000414797.1, ENST00000440156.5
    Conserved Domains (3) summary
    TIGR00834
    Location:122 → 1131
    ae; anion exchange protein
    pfam00955
    Location:571 → 1084
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:150 → 528
    Band_3_cyto; Band 3 cytoplasmic domain

  5. NM_001321105.2 → NP_001308034.1  sodium bicarbonate cotransporter 3 isoform f

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, EU499349, EU934247, EU934249, FJ178574
    Consensus CDS
    CCDS82748.1
    UniProtKB/TrEMBL
    B5M450, E9PFN4
    Related
    ENSP00000406804.1, ENST00000445684.5
    Conserved Domains (3) summary
    TIGR00834
    Location:122 → 1131
    ae; anion exchange protein
    pfam00955
    Location:571 → 1084
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:150 → 528
    Band_3_cyto; Band 3 cytoplasmic domain

  6. NM_001321106.2 → NP_001308035.1  sodium bicarbonate cotransporter 3 isoform g

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, EU499349, EU934249, FJ178574
    Consensus CDS
    CCDS82751.1
    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000406605.1, ENST00000446700.5
    Conserved Domains (3) summary
    TIGR00834
    Location:118 → 1127
    ae; anion exchange protein
    pfam00955
    Location:567 → 1080
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:146 → 524
    Band_3_cyto; Band 3 cytoplasmic domain

  7. NM_001321107.2 → NP_001308036.1  sodium bicarbonate cotransporter 3 isoform h

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, EU499349, EU934249
    Consensus CDS
    CCDS82750.1
    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000394252.1, ENST00000437179.5
    Conserved Domains (3) summary
    TIGR00834
    Location:118 → 1016
    ae; anion exchange protein
    pfam00955
    Location:456 → 969
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:146 → 413
    Band_3_cyto; Band 3 cytoplasmic domain

  8. NM_001321108.2 → NP_001308037.1  sodium bicarbonate cotransporter 3 isoform i

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, EU499349, EU934249, GU354308
    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000533106.1, ENST00000863047.1
    Conserved Domains (3) summary
    TIGR00834
    Location:122 → 1020
    ae; anion exchange protein
    pfam00955
    Location:460 → 973
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:150 → 417
    Band_3_cyto; Band 3 cytoplasmic domain

  9. NM_003615.5 → NP_003606.3  sodium bicarbonate cotransporter 3 isoform a

    See identical proteins and their annotated locations for NP_003606.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant encodes isoform a.
    Source sequence(s)
    AA569234, AC099535, AF047033, AK310865, AL389947, EU934250
    Consensus CDS
    CCDS33721.1
    UniProtKB/Swiss-Prot
    A6NIA8, B2CI53, B5M449, B5M451, B5M452, B5M453, B6DY52, B6DY53, C9JST9, D3K174, D3K175, O60350, Q6AHZ9, Q9HC88, Q9UIB9, Q9Y6M7
    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000295736.5, ENST00000295736.9
    Conserved Domains (3) summary
    TIGR00834
    Location:113 → 1135
    ae; anion exchange protein
    pfam00955
    Location:575 → 1088
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:141 → 532
    Band_3_cyto; Band 3 cytoplasmic domain

RNA

  1. NR_135541.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, FJ178574

  2. NR_135542.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, FJ178574, FJ178575

  3. NR_135543.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, FJ178574, FJ178575

  4. NR_135544.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA569234, AF047033, AF053755, AK309734, AK310865, AL389947, EU499349, EU934249, FJ178574, GU354307

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    27372723..27484384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017007527.3 → XP_016863016.1  sodium bicarbonate cotransporter 3 isoform X9

    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000605605.1, ENST00000935546.1

  2. XM_047449246.1 → XP_047305202.1  sodium bicarbonate cotransporter 3 isoform X3

    UniProtKB/TrEMBL
    B5M450

  3. XM_006713421.4 → XP_006713484.1  sodium bicarbonate cotransporter 3 isoform X1

    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000605608.1, ENST00000935549.1
    Conserved Domains (3) summary
    TIGR00834
    Location:118 → 1140
    ae; anion exchange protein
    pfam00955
    Location:580 → 1093
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:146 → 537
    Band_3_cyto; Band 3 cytoplasmic domain

  4. XM_011534263.4 → XP_011532565.1  sodium bicarbonate cotransporter 3 isoform X8

    UniProtKB/TrEMBL
    B5M450
    Conserved Domains (3) summary
    TIGR00834
    Location:122 → 1007
    ae; anion exchange protein
    pfam00955
    Location:447 → 960
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:150 → 404
    Band_3_cyto; Band 3 cytoplasmic domain

  5. XM_011534265.3 → XP_011532567.1  sodium bicarbonate cotransporter 3 isoform X11

    UniProtKB/TrEMBL
    B5M450
    Conserved Domains (3) summary
    TIGR00834
    Location:122 → 1020
    ae; anion exchange protein
    pfam00955
    Location:460 → 973
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:150 → 417
    Band_3_cyto; Band 3 cytoplasmic domain

  6. XM_011534258.3 → XP_011532560.1  sodium bicarbonate cotransporter 3 isoform X4

    UniProtKB/TrEMBL
    B5M450
    Related
    ENSP00000633994.1, ENST00000963935.1
    Conserved Domains (3) summary
    TIGR00834
    Location:122 → 1144
    ae; anion exchange protein
    pfam00955
    Location:584 → 1097
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:150 → 541
    Band_3_cyto; Band 3 cytoplasmic domain

  7. XM_047449247.1 → XP_047305203.1  sodium bicarbonate cotransporter 3 isoform X6

    UniProtKB/TrEMBL
    B5M450

  8. XM_005265600.6 → XP_005265657.1  sodium bicarbonate cotransporter 3 isoform X10

    UniProtKB/TrEMBL
    C9JRP1
    Conserved Domains (3) summary
    TIGR00834
    Location:113 → 998
    ae; anion exchange protein
    pfam00955
    Location:438 → 951
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:141 → 395
    Band_3_cyto; Band 3 cytoplasmic domain

  9. XM_011534261.4 → XP_011532563.1  sodium bicarbonate cotransporter 3 isoform X5

    UniProtKB/TrEMBL
    B5M450
    Conserved Domains (3) summary
    TIGR00834
    Location:113 → 1122
    ae; anion exchange protein
    pfam00955
    Location:562 → 1075
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:141 → 519
    Band_3_cyto; Band 3 cytoplasmic domain

  10. XM_005265598.6 → XP_005265655.1  sodium bicarbonate cotransporter 3 isoform X7

    UniProtKB/TrEMBL
    C9JRP1
    Conserved Domains (3) summary
    TIGR00834
    Location:113 → 1011
    ae; anion exchange protein
    pfam00955
    Location:451 → 964
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:141 → 408
    Band_3_cyto; Band 3 cytoplasmic domain

  11. XM_011534256.4 → XP_011532558.1  sodium bicarbonate cotransporter 3 isoform X2

    UniProtKB/TrEMBL
    B5M450
    Conserved Domains (3) summary
    TIGR00834
    Location:113 → 1135
    ae; anion exchange protein
    pfam00955
    Location:575 → 1088
    HCO3_cotransp; HCO3- transporter family
    pfam07565
    Location:141 → 532
    Band_3_cyto; Band 3 cytoplasmic domain

  12. XM_017007529.1 → XP_016863018.1  sodium bicarbonate cotransporter 3 isoform X12

    UniProtKB/TrEMBL
    H7C3C4
    Related
    ENSP00000411031.1, ENST00000419036.5

  13. XM_017007528.1 → XP_016863017.1  sodium bicarbonate cotransporter 3 isoform X12

    UniProtKB/TrEMBL
    H7C3C4

  14. XM_047449248.1 → XP_047305204.1  sodium bicarbonate cotransporter 3 isoform X13

    Related
    ENSP00000409418.1, ENST00000437266.5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    27374872..27486481 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054348464.1 → XP_054204439.1  sodium bicarbonate cotransporter 3 isoform X9

    UniProtKB/TrEMBL
    B5M450

  2. XM_054348458.1 → XP_054204433.1  sodium bicarbonate cotransporter 3 isoform X3

    UniProtKB/TrEMBL
    B5M450

  3. XM_054348456.1 → XP_054204431.1  sodium bicarbonate cotransporter 3 isoform X1

    UniProtKB/TrEMBL
    B5M450

  4. XM_054348463.1 → XP_054204438.1  sodium bicarbonate cotransporter 3 isoform X8

    UniProtKB/TrEMBL
    B5M450

  5. XM_054348466.1 → XP_054204441.1  sodium bicarbonate cotransporter 3 isoform X11

    UniProtKB/TrEMBL
    B5M450

  6. XM_054348459.1 → XP_054204434.1  sodium bicarbonate cotransporter 3 isoform X4

    UniProtKB/TrEMBL
    B5M450

  7. XM_054348461.1 → XP_054204436.1  sodium bicarbonate cotransporter 3 isoform X6

    UniProtKB/TrEMBL
    B5M450

  8. XM_054348465.1 → XP_054204440.1  sodium bicarbonate cotransporter 3 isoform X10

    UniProtKB/TrEMBL
    C9JRP1

  9. XM_054348460.1 → XP_054204435.1  sodium bicarbonate cotransporter 3 isoform X5

    UniProtKB/TrEMBL
    B5M450

  10. XM_054348462.1 → XP_054204437.1  sodium bicarbonate cotransporter 3 isoform X7

    UniProtKB/TrEMBL
    C9JRP1

  11. XM_054348457.1 → XP_054204432.1  sodium bicarbonate cotransporter 3 isoform X2

    UniProtKB/TrEMBL
    B5M450

  12. XM_054348468.1 → XP_054204443.1  sodium bicarbonate cotransporter 3 isoform X12

    UniProtKB/TrEMBL
    H7C3C4

  13. XM_054348467.1 → XP_054204442.1  sodium bicarbonate cotransporter 3 isoform X12

    UniProtKB/TrEMBL
    H7C3C4

  14. XM_054348469.1 → XP_054204444.1  sodium bicarbonate cotransporter 3 isoform X13

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Y6M7.2 GenPept UniProtKB/Swiss-Prot:Q9Y6M7

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