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proS proline--tRNA ligase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949116, updated on 6-May-2021

Summary

Gene symbol
proS
Gene description
proline--tRNA ligase
Primary source
ASAP:ABE-0000657
Locus tag
b0194
See related
ECOCYC:EG10770
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
drp; drpA; ECK0194
Summary
An insertion domain (248-393) in ProS is homologous to YeaK and YbaK. [More information is available at EcoGene: EG10770]. Prolyl-tRNA synthetase (ProRS) is a member of the family of aminoacyl-tRNA synthetases, which interpret the genetic code by covalently linking amino acids to their specific tRNA molecules. [More information is available at EcoCyc: EG10770].
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Genomic context

Sequence:
NC_000913.3 (217057..218775, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sensor lipoprotein NlpE Neighboring gene peptidase C92 family protein YaeF Neighboring gene tRNA m(6)t(6)A37 methyltransferase Neighboring gene sensor lipoprotein RcsF Neighboring gene L-methionine/D-methionine ABC transporter membrane anchored binding protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables Ala-tRNA(Pro) hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables aminoacyl-tRNA editing activity IEA
Inferred from Electronic Annotation
more info
 
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables proline-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables proline-tRNA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables proline-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
proline--tRNA ligase
NP_414736.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    217057..218775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414736.1 proline--tRNA ligase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414736.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P16659
    Conserved Domains (1) summary
    PRK09194
    Location:1571
    PRK09194; prolyl-tRNA synthetase; Provisional
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