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mak fructokinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949086, updated on 19-Sep-2024

Summary

Official Symbol
mak
Official Full Name
fructokinase
Primary source
ECOCYC:EG11288
Locus tag
b0394
See related
ASAP:ABE-0001372
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0389; yajF
Summary
Mak also has low level glucokinase activity; fructose is a much substrate than glucose in vitro. [More information is available at EcoGene: EG11288]. In the absence of the usual PTS-mediated route of fructose uptake, Mak catalyzes phosphorylation of fructose after its entry into the cell via PtsGF . [More information is available at EcoCyc: EG11288].
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Genomic context

Sequence:
NC_000913.3 (410144..411052)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene protein YkiD Neighboring gene nucleoid-associated protein RdgC Neighboring gene putative transport protein AraJ Neighboring gene ATP-dependent structure-specific DNA nuclease - SbcC subunit Neighboring gene ATP-dependent structure-specific DNA nuclease - SbcD subunit

Pathways from PubChem

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables fructokinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables fructokinase activity IEA
Inferred from Electronic Annotation
more info
 
enables hexokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables mannokinase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    410144..411052
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414928.2 fructokinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414928.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376X5F1, A0A8T3UGY4
    Conserved Domains (1) summary
    PRK09557
    Location:1301
    PRK09557; fructokinase; Reviewed