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lacY lactose permease [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949083, updated on 22-Sep-2022

Summary

Gene symbol
lacY
Gene description
lactose permease
Primary source
ASAP:ABE-0001181
Locus tag
b0343
See related
ECOCYC:EG10526
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0340
Summary
Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG10526]. The lactose permease LacY is a lactose/proton symporter, responsible for the uptake of lactose and other galactosides. [More information is available at EcoCyc: EG10526].
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Genomic context

Sequence:
NC_000913.3 (361926..363179, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cyanate transporter Neighboring gene galactoside O-acetyltransferase Neighboring gene beta-galactosidase Neighboring gene DNA-binding transcriptional repressor LacI

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables carbohydrate:proton symporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables carbohydrate:proton symporter activity IEA
Inferred from Electronic Annotation
more info
 
enables lactose binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lactose binding IDA
Inferred from Direct Assay
more info
PubMed 
enables lactose:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lactose:proton symporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lactose:proton symporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in carbohydrate transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within carbohydrate transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in carbohydrate transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lactose transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in organic substance transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    361926..363179 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414877.1 lactose permease [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414877.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P02920
    Conserved Domains (1) summary
    pfam01306
    Location:1413
    LacY_symp; LacY proton/sugar symporter