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caiA crotonobetainyl-CoA reductase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949064, updated on 6-May-2021

Summary

Gene symbol
caiA
Gene description
crotonobetainyl-CoA reductase
Primary source
ASAP:ABE-0000139
Locus tag
b0039
See related
ECOCYC:EG11560
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0040; yaaO
Summary
Crotonobetaine reductase catalyzes the final reaction in the metabolization of L-carnitine. [More information is available at EcoCyc: EG11560].
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Genomic context

Sequence:
NC_000913.3 (39244..40386, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene carnitine--CoA ligase Neighboring gene gamma-butyrobetainyl-CoA:carnitine CoA transferase Neighboring gene L-carnitine:gamma-butyrobetaine antiporter Neighboring gene putative electron transfer flavoprotein FixA

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables acyl-CoA dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-CH group of donors IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within carnitine metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
crotonobetainyl-CoA reductase
NP_414581.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    39244..40386 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414581.1 crotonobetainyl-CoA reductase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414581.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P60584
    Conserved Domains (1) summary
    PRK03354
    Location:1380
    PRK03354; crotonobetainyl-CoA dehydrogenase; Validated
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