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coaE dephospho-CoA kinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949060, updated on 3-Dec-2024

Summary

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Official Symbol
coaE
Official Full Name
dephospho-CoA kinase
Primary source
ECOCYC:EG12312
Locus tag
b0103
See related
ASAP:ABE-0000357
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0103; yacE
Summary
coaE is essential for growth as tested by genetic footprinting. [More information is available at EcoGene: EG12312]. Dephospho-CoA kinase catalyzes the final step in coenzyme A biosynthesis . [More information is available at EcoCyc: EG12312].
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Genomic context

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Sequence:
NC_000913.3 (112599..113219, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA gyrase inhibitor YacG Neighboring gene cell division factor ZapD Neighboring gene protein YacM Neighboring gene GMP reductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of a trimeric form of dephosphocoenzyme A kinase from Escherichia coli. O'Toole N, et al. Protein Sci, 2003 Feb. PMID 12538896, Free PMC Article
  2. Identification of yacE (coaE) as the structural gene for dephosphocoenzyme A kinase in Escherichia coli K-12. Mishra P, et al. J Bacteriol, 2001 May. PMID 11292795, Free PMC Article
  3. Structural analysis of a set of proteins resulting from a bacterial genomics project. Badger J, et al. Proteins, 2005 Sep 1. PMID 16021622
  4. Genetic footprinting in bacteria. Hare RS, et al. J Bacteriol, 2001 Mar. PMID 11160101, Free PMC Article
  5. Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region. Fujita N, et al. Nucleic Acids Res, 1994 May 11. PMID 8202364, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables dephospho-CoA kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dephospho-CoA kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables dephospho-CoA kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in coenzyme A biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within coenzyme A biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in coenzyme A biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dephospho-CoA kinase
NP_414645.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    112599..113219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414645.1 dephospho-CoA kinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414645.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376ME76, A0A8T6Q544
    Conserved Domains (1) summary
    PRK00081
    Location:1 → 193
    coaE; dephospho-CoA kinase; Reviewed
Nucleotide Protein
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