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galS DNA-binding transcriptional dual regulator GalS [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949043, updated on 23-Nov-2023

Summary

Gene symbol
galS
Gene description
DNA-binding transcriptional dual regulator GalS
Primary source
ASAP:ABE-0007110
Locus tag
b2151
See related
ECOCYC:EG10365
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2144; mglD
Summary
The "Galactose isorepressor," GalS, is a DNA-binding transcription factor that represses transcription of the operons involved in transport and catabolism of D-galactose . [More information is available at EcoCyc: EG10365].
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Genomic context

Sequence:
NC_000913.3 (2240628..2241668, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-galactose/methyl-galactoside ABC transporter ATP binding subunit Neighboring gene D-galactose/methyl-galactoside ABC transporter periplasmic binding protein Neighboring gene DUF418 domain-containing protein YeiB Neighboring gene GTP cyclohydrolase 1

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA-binding transcriptional dual regulator GalS

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2240628..2241668 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416656.1 DNA-binding transcriptional dual regulator GalS [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416656.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A895NXH4
    Conserved Domains (1) summary
    PRK10401
    Location:1346
    PRK10401; HTH-type transcriptional regulator GalS