U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

galS DNA-binding transcriptional dual regulator GalS [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949043, updated on 30-Jul-2025
Official Symbol
galS
Official Full Name
DNA-binding transcriptional dual regulator GalS
Primary source
ECOCYC:EG10365
Locus tag
b2151
See related
ASAP:ABE-0007110
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2144; mglD
Summary
The "Galactose isorepressor," GalS, is a DNA-binding transcription factor that represses transcription of the operons involved in transport and catabolism of D-galactose . [More information is available at EcoCyc: EG10365].
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (2240628..2241668, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-galactose/methyl-galactoside ABC transporter ATP binding subunit Neighboring gene D-galactose/methyl-galactoside ABC transporter periplasmic binding protein Neighboring gene DUF418 domain-containing protein YeiB Neighboring gene GTP cyclohydrolase 1

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Adaptive mgl-regulatory mutations and genetic diversity evolving in glucose-limited Escherichia coli populations. Notley-McRobb L, et al. Environ Microbiol, 1999 Feb. PMID 11207716
  2. Regulation of the Escherichia coli methylgalactoside transport system by gene mglD. Robbins AR. J Bacteriol, 1975 Jul. PMID 1095564, Free PMC Article
  3. Interpretations of five monoclonal immunoassays of lutropin and follitropin: effects of normalization with WHO standard. Vermes I, et al. Clin Chem, 1991 Mar. PMID 1900742
  4. Locations and orientations on the Escherichia coli physical map of the mgl operon and galS, a new locus for galactose ultrainduction. Weickert MJ, et al. J Bacteriol, 1991 Dec. PMID 1938936, Free PMC Article
  5. DNA recognition and the code. Müller-Hill B, et al. Nature, 1994 Jun 23. PMID 8208287

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: Functional characterization of roles of GalR and GalS as regulators of the gal regulon.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional dual regulator GalS

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2240628..2241668 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416656.1 DNA-binding transcriptional dual regulator GalS

    See identical proteins and their annotated locations for NP_416656.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A895NXH4
    Conserved Domains (1) summary
    PRK10401
    Location:1 → 346
    PRK10401; HTH-type transcriptional regulator GalS
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.