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aslB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949013, updated on 24-Aug-2024

Summary

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Official Symbol
aslB
Primary source
ECOCYC:EG10090
Locus tag
b3800
See related
ASAP:ABE-0012408
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
atsB; ECK3793; gppB
Summary
Radical SAM superfamily. [More information is available at EcoGene: EG10090]. AslB is a member of the anaerobic sulfatase maturation enzyme subfamily of the Radical SAM superfamily of enzymes . [More information is available at EcoCyc: EG10090].
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Genomic context

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Sequence:
NC_000913.3 (3982958..3984193)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene tRNA-Pro Neighboring gene putative sulfatase AslA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Anaerobic sulfatase maturase AslB from Escherichia coli activates human recombinant iduronate-2-sulfate sulfatase (IDS) and N-acetylgalactosamine-6-sulfate sulfatase (GALNS). Alméciga-Díaz CJ, et al. Gene, 2017 Nov 15. PMID 28882567
  2. Spacing mutations between the Escherichia coli pBAD RNA polymerase binding site and the araC (I) induction site. Hendrickson W, et al. Nucleic Acids Res, 1983 Mar 25. PMID 6300782, Free PMC Article
  3. A novel mucin-sulphatase activity found in Burkholderia cepacia and Pseudomonas aeruginosa. Jansen HJ, et al. J Med Microbiol, 1999 Jun. PMID 10359304
  4. Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility. Hanson SR, et al. Angew Chem Int Ed Engl, 2004 Nov 5. PMID 15493058
  5. First evidences for a third sulfatase maturation system in prokaryotes from E. coli aslB and ydeM deletion mutants. Benjdia A, et al. FEBS Lett, 2007 Mar 6. PMID 17303125

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cys-type sulfatases can mature only in aerobic conditions, and knocking-out of aslB, ydeM and yidF does not impair Cys-type sulfatase maturation.
    Title: First evidences for a third sulfatase maturation system in prokaryotes from E. coli aslB and ydeM deletion mutants.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein maturation ISO
Inferred from Sequence Orthology
more info
 PubMed 
acts_upstream_of_or_within protein maturation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
putative anaerobic sulfatase maturation enzyme AslB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3982958..3984193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026259.1 putative anaerobic sulfatase maturation enzyme AslB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026259.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7EIE1
    Conserved Domains (1) summary
    TIGR03942
    Location:11 → 391
    sulfatase_rSAM; anaerobic sulfatase-maturating enzyme
Nucleotide Protein
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