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hybD hydrogenase 2 maturation protease [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948982, updated on 6-May-2021

Summary

Gene symbol
hybD
Gene description
hydrogenase 2 maturation protease
Primary source
ASAP:ABE-0009826
Locus tag
b2993
See related
ECOCYC:EG11802
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2987
Summary
Based on its similarity to the processing enzyme for hydrogenase 3, HycI, HybD is predicted to be an endopeptidase involved in the maturation of the large subunit of hydrogenase 2 (HybC) . [More information is available at EcoCyc: EG11802].
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Genomic context

Sequence:
NC_000913.3 (3140792..3141286, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase maturation factor HybG Neighboring gene hydrogenase maturation protein HybF Neighboring gene hydrogenase 2-specific chaperone Neighboring gene hydrogenase 2 large subunit Neighboring gene hydrogenase 2 membrane subunit Neighboring gene hydrogenase 2 iron-sulfur protein Neighboring gene hydrogenase 2 small subunit

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables enzyme activator activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular protein modification process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within positive regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
involved_in protein processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within protein processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein processing ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
hydrogenase 2 maturation protease

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3140792..3141286 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417467.1 hydrogenase 2 maturation protease [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417467.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P37182
    Conserved Domains (1) summary
    PRK10466
    Location:1164
    hybD; HyaD/HybD family hydrogenase maturation endopeptidase
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