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srlB sorbitol-specific PTS enzyme IIA component [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948971, updated on 23-Apr-2026
Official Symbol
srlB
Official Full Name
sorbitol-specific PTS enzyme IIA component
Primary source
ECOCYC:EG10970
Locus tag
b2704
See related
ASAP:ABE-0008894
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2699; gutB
Summary
[More information is available at EcoCyc: EG10970].
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Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (2827362..2827733)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene membrane-bound lytic murein transglycosylase B Neighboring gene sorbitol-specific PTS enzyme IIC2 component Neighboring gene sorbitol-specific PTS enzyme IIBC1 component Neighboring gene sorbitol-6-phosphate 2-dehydrogenase Neighboring gene DNA-binding transcriptional activator GutM

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Molecular population genetics of Escherichia coli: DNA sequence diversity at the celC, crr, and gutB loci of natural isolates. Hall BG, et al. Mol Biol Evol, 1992 Jul. PMID 1630305
  2. Proposed topology of the glucitol permeases of Escherichia coli and Clostridium acetobutylicum. Reizer J, et al. Curr Microbiol, 1996 Nov. PMID 8875915
  3. Physical and genetic characterization of the glucitol operon in Escherichia coli. Yamada M, et al. J Bacteriol, 1987 Jul. PMID 3036766, Free PMC Article
  4. Genetic analysis of the Escherichia coli K-12 srl region. McEntee K. J Bacteriol, 1977 Dec. PMID 336611, Free PMC Article
  5. Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features. Yamamoto Y, et al. DNA Res, 1997 Apr 28. PMID 9205837

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables kinase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables phosphotransferase activity, alcohol group as acceptor IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in sorbitol transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Preferred Names
sorbitol-specific PTS enzyme IIA component
NP_417184.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2827362..2827733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417184.1 sorbitol-specific PTS enzyme IIA component

    See identical proteins and their annotated locations for NP_417184.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    W1X7T1
    Conserved Domains (1) summary
    PRK10377
    Location:1 → 120
    PRK10377; PTS glucitol/sorbitol transporter subunit IIA
Nucleotide Protein
Heading Accession and Version

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