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bglJ DNA-binding transcriptional regulator BglJ [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948889, updated on 25-Jun-2025
Official Symbol
bglJ
Official Full Name
DNA-binding transcriptional regulator BglJ
Primary source
ECOCYC:G7948
Locus tag
b4366
See related
ASAP:ABE-0014324
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4356; yjjR
Summary
BglJ is a positive DNA-binding transcriptional regulator of transport and utilization of the aromatic -glucosides arbutin and salicin . [More information is available at EcoCyc: G7948].
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Sequence:
NC_000913.3 (4604160..4604837)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene primosomal protein DnaT Neighboring gene putative succinate exporter YjjB Neighboring gene putative succinate exporter YjjP Neighboring gene DNA-binding transcriptional repressor YjjQ Neighboring gene ferric-siderophore reductase FhuF Neighboring gene DUF1435 domain-containing protein YjjZ

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Correlation of Antagonistic Regulation of leuO Transcription with the Cellular Levels of BglJ-RcsB and LeuO in Escherichia coli. Breddermann H, et al. Front Cell Infect Microbiol, 2016. PMID 27695690, Free PMC Article
  2. RcsB-BglJ activates the Escherichia coli leuO gene, encoding an H-NS antagonist and pleiotropic regulator of virulence determinants. Stratmann T, et al. Mol Microbiol, 2012 Mar. PMID 22295907
  3. Regulation of the yjjQ-bglJ operon, encoding LuxR-type transcription factors, and the divergent yjjP gene by H-NS and LeuO. Stratmann T, et al. J Bacteriol, 2008 Feb. PMID 18055596, Free PMC Article
  4. A mutation in a new gene, bglJ, activates the bgl operon in Escherichia coli K-12. Giel M, et al. Genetics, 1996 Jun. PMID 8725214, Free PMC Article
  5. The leuO gene product has a latent ability to relieve bgl silencing in Escherichia coli. Ueguchi C, et al. J Bacteriol, 1998 Jan. PMID 9422614, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BglJ-RcsB activates leuO, while LeuO inhibits activation by BglJ-RcsB. Furthermore, LeuO activates expression of bglJ, which is likewise H-NS repressed.
    Title: Correlation of Antagonistic Regulation of leuO Transcription with the Cellular Levels of BglJ-RcsB and LeuO in Escherichia coli.
  2. BglJ-RcsB is a pleiotropic transcriptional activator that coordinates regulation with global regulators including CRP, LeuO and HNS.
    Title: Transcriptional regulation by BglJ-RcsB, a pleiotropic heteromeric activator in Escherichia coli.
  3. RcsB-BglJ binds to the leuO promoter region and activates one of two leuO promoters.
    Title: RcsB-BglJ activates the Escherichia coli leuO gene, encoding an H-NS antagonist and pleiotropic regulator of virulence determinants.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of carbohydrate catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to radiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of transcription regulator complex IPI
Inferred from Physical Interaction
more info
 PubMed 
Preferred Names
DNA-binding transcriptional regulator BglJ

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4604160..4604837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418786.4 DNA-binding transcriptional regulator BglJ [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418786.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2X1MK46, A0A376MQX6, A0A8S7EGF3, A0AAN3NWH0
    Conserved Domains (1) summary
    PRK11475
    Location:19 → 225
    PRK11475; DNA-binding transcriptional activator BglJ; Provisional
Nucleotide Protein
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Gene LinkOut

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