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uxuR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948849, updated on 24-Aug-2024

Summary

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Official Symbol
uxuR
Primary source
ASAP:ABE-0014179
Locus tag
b4324
See related
ECOCYC:EG20249
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4315
Summary
UxuR regulon. [More information is available at EcoGene: EG20249]. UxuR is a protein that belongs to the GntR family and participates as a regulator in controlling several genes involved in carbon uptake. [More information is available at EcoCyc: EG20249].
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Genomic context

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Sequence:
NC_000913.3 (4554576..4555349)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-mannonate dehydratase Neighboring gene D-mannonate oxidoreductase Neighboring gene DUF2686 domain-containing protein YjiC Neighboring gene protein YtiC Neighboring gene protein YtiD

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple regulation involved in the expression of the uxuR regulatory gene in Escherichia coli K-12. Ritzenthaler P, et al. Mol Gen Genet, 1983. PMID 6406797
  2. Use of in vitro gene fusions to study the uxuR regulatory gene in Escherichia coli K-12: direction of transcription and regulation of its expression. Ritzenthaler P, et al. J Bacteriol, 1982 Jun. PMID 6281232, Free PMC Article
  3. Control of hexuronate metabolism in Escherichia coli by the two interdependent regulators, ExuR and UxuR: derepression by heterodimer formation. Tutukina MN, et al. Microbiology (Reading), 2016 Jul. PMID 27129867
  4. GntP is the Escherichia coli Fructuronic acid transporter and belongs to the UxuR regulon. Bates Utz C, et al. J Bacteriol, 2004 Nov. PMID 15516583, Free PMC Article
  5. Negative dominant mutations of the uidR gene in Escherichia coli: genetic proof for a cooperative regulation of uidA expression. Blanco C, et al. Genetics, 1986 Feb. PMID 3079718, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. UxuR is essential for rapid growth with D-glucuronate as the primary source of carbon and energy.
    Title: Control of hexuronate metabolism in Escherichia coli by the two interdependent regulators, ExuR and UxuR: derepression by heterodimer formation.
  2. a module of sugar acid catabolism whose physiological role is for growth on fructuronate
    Title: GntP is the Escherichia coli Fructuronic acid transporter and belongs to the UxuR regulon.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-binding transcriptional repressor UxuR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4554576..4555349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418744.1 DNA-binding transcriptional repressor UxuR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418744.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N8NGI1
    Conserved Domains (1) summary
    PRK10225
    Location:1 → 257
    PRK10225; Uxu operon transcriptional regulator
Nucleotide Protein
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Gene LinkOut

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