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nanY 2,7-anhydro-N-acetylneuraminate hydratase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948808, updated on 25-Jun-2025
Official Symbol
nanY
Official Full Name
2,7-anhydro-N-acetylneuraminate hydratase
Primary source
ECOCYC:G7901
Locus tag
b4280
See related
ASAP:ABE-0014027
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4270; yjhC
Summary
YjhC may be involved in metabolism of sialic acid; see . [More information is available at EcoCyc: G7901].
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Sequence:
NC_000913.3 (4505287..4506405)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene IS4 family putative transposase Neighboring gene sialic acid transporter NanX Neighboring gene uncharacterized protein YthA Neighboring gene pseudo

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The putative Escherichia coli dehydrogenase YjhC metabolises two dehydrated forms of N-acetylneuraminate produced by some sialidases. Kentache T, et al. Biosci Rep, 2020 Jun 26. PMID 32542330, Free PMC Article
  2. On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism. Horne CR, et al. Proteins, 2020 May. PMID 31697432
  3. Distant cis-active sequences and sialic acid control the expression of fimB in Escherichia coli K-12. El-Labany S, et al. Mol Microbiol, 2003 Aug. PMID 12890032
  4. Studying protein complexes by the yeast two-hybrid system. Rajagopala SV, et al. Methods, 2012 Dec. PMID 22841565, Free PMC Article
  5. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism.
    Title: On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables hydro-lyase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within N-acetylneuraminate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Preferred Names
2,7-anhydro-N-acetylneuraminate hydratase

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4505287..4506405
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418700.2 2,7-anhydro-N-acetylneuraminate hydratase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418700.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0B0VHQ2, A0A828TYP3
    Conserved Domains (1) summary
    COG0673
    Location:1 → 364
    MviM; Predicted dehydrogenase [General function prediction only]
Nucleotide Protein
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