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fdnH formate dehydrogenase N subunit beta [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948794, updated on 4-Feb-2026
Official Symbol
fdnH
Official Full Name
formate dehydrogenase N subunit beta
Primary source
ECOCYC:EG11228
Locus tag
b1475
See related
ASAP:ABE-0004919
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1469
Summary
FdnH is co-exported bound to Tat substrate FdnG. [More information is available at EcoGene: EG11228]. FdnH contains four [4Fe-4S] clusters and one C-terminal transmembrane helix . [More information is available at EcoCyc: EG11228].
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Sequence:
NC_000913.3 (1550461..1551345)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene amino acid exporter YddG Neighboring gene formate dehydrogenase N subunit alpha Neighboring gene formate dehydrogenase N subunit gamma Neighboring gene DNA-binding transcriptional regulator YddM Neighboring gene ethanol dehydrogenase/alcohol dehydrogenase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Escherichia coli formate dehydrogenase mutants with altered selenopolymer profiles. Cox JC. Arch Microbiol, 1989. PMID 2684082
  2. The purification and properties of formate dehydrogenase and nitrate reductase from Escherichia coli. Enoch HG, et al. J Biol Chem, 1975 Sep 10. PMID 1099093
  3. Localization of upstream sequence elements required for nitrate and anaerobic induction of fdn (formate dehydrogenase-N) operon expression in Escherichia coli K-12. Li J, et al. J Bacteriol, 1992 Aug. PMID 1629153, Free PMC Article
  4. Purification and crystallization of the respiratory complex formate dehydrogenase-N from Escherichia coli. Jormakka M, et al. Acta Crystallogr D Biol Crystallogr, 2002 Jan. PMID 11752799
  5. Nitrate-inducible formate dehydrogenase in Escherichia coli K-12. II. Evidence that a mRNA stem-loop structure is essential for decoding opal (UGA) as selenocysteine. Berg BL, et al. J Biol Chem, 1991 Nov 25. PMID 1834670

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables electron transfer activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables formate dehydrogenase (quinone) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables formate dehydrogenase (quinone) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables formate dehydrogenase (quinone) activity IEA
Inferred from Electronic Annotation
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anaerobic electron transport chain NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in anaerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in anaerobic respiration IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within anaerobic respiration IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in cellular respiration IEA
Inferred from Electronic Annotation
more info
  
involved_in formate oxidation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within formate oxidation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in formate oxidation IEA
Inferred from Electronic Annotation
more info
  
involved_in formate oxidation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in heme oxidation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of formate dehydrogenase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of formate dehydrogenase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of formate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
  
located_in membrane HDA PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
formate dehydrogenase N subunit beta
NP_415992.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1550461..1551345
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415992.1 formate dehydrogenase N subunit beta

    See identical proteins and their annotated locations for NP_415992.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2H4U051, A0A6C9QFE0
    Conserved Domains (1) summary
    TIGR01582
    Location:7 → 290
    FDH-beta; formate dehydrogenase, beta subunit, Fe-S containing
Nucleotide Protein
Heading Accession and Version

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