U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mgtA Mg(2(+)) importing P-type ATPase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948778, updated on 19-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
mgtA
Official Full Name
Mg(2(+)) importing P-type ATPase
Primary source
ECOCYC:EG12525
Locus tag
b4242
See related
ASAP:ABE-0013883
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
atmA; corB; ECK4237; mgt; mtg
Summary
Mg(2+) stimulon-PhoPQ regulon, EvgAS-PhoPQ cascade enhanced-expression subset. [More information is available at EcoGene: EG12525]. MgtA is a P-type ATPase involved in the uptake of magnesium ion . [More information is available at EcoCyc: EG12525].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (4467625..4470321)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor TreR Neighboring gene leader peptide MgtL Neighboring gene enamine/imine deaminase, redox-regulated chaperone Neighboring gene aspartate carbamoyltransferase, PyrI subunit

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The magnesium transporter A is activated by cardiolipin and is highly sensitive to free magnesium in vitro. Subramani S, et al. Elife, 2016 Jan 18. PMID 26780187, Free PMC Article
  2. The structure of Mg-ATPase nucleotide-binding domain at 1.6 A resolution reveals a unique ATP-binding motif. Håkansson KO. Acta Crystallogr D Biol Crystallogr, 2009 Nov. PMID 19923713
  3. Regulation of magnesium homeostasis in Salmonella: Mg(2+) targets the mgtA transcript for degradation by RNase E. Spinelli SV, et al. FEMS Microbiol Lett, 2008 Mar. PMID 18248433
  4. A Mg2+-responding RNA that controls the expression of a Mg2+ transporter. Groisman EA, et al. Cold Spring Harb Symp Quant Biol, 2006. PMID 17381304
  5. An RNA sensor for intracellular Mg(2+). Cromie MJ, et al. Cell, 2006 Apr 7. PMID 16615891

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These findings indicate that MgtA may act as a sensor as well as a transporter of Mg(2+).
    Title: The magnesium transporter A is activated by cardiolipin and is highly sensitive to free magnesium in vitro.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled monoatomic cation transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables P-type ion transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables P-type ion transporter activity TAS
Traceable Author Statement
more info
 PubMed 
enables P-type magnesium transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables P-type magnesium transporter activity ISO
Inferred from Sequence Orthology
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to magnesium ion IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within magnesium ion transmembrane transport ISO
Inferred from Sequence Orthology
more info
 PubMed 
involved_in magnesium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Mg(2(+)) importing P-type ATPase
NP_418663.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4467625..4470321
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418663.1 Mg(2(+)) importing P-type ATPase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418663.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7EKB8
    Conserved Domains (1) summary
    PRK10517
    Location:1 → 898
    PRK10517; magnesium-transporting P-type ATPase MgtA
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.