U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

argI ornithine carbamoyltransferase ArgI [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948774, updated on 30-Jul-2025
Official Symbol
argI
Official Full Name
ornithine carbamoyltransferase ArgI
Primary source
ECOCYC:EG10069
Locus tag
b4254
See related
ASAP:ABE-0013927
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4247
Summary
argI and argF have same enzyme activity. [More information is available at EcoGene: EG10069]. In the test tube, not in the cell, a family of four isoenzymes forms by assortment of two closely similar polypeptides, the chain F-monomer and chain I-monomer, to give active trimers FFF, FFI, FII, and III. [More information is available at EcoCyc: EG10069].
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (4477307..4478311, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF386 domain-containing toxin-antitoxin biofilm protein TabA Neighboring gene protein YjgL Neighboring gene ribonuclease E inhibitor protein B Neighboring gene putative N-acetyltransferase YjgM

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables amino acid binding IEA
Inferred from Electronic Annotation
more info
  
enables carboxyl- or carbamoyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ornithine carbamoyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ornithine carbamoyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ornithine carbamoyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-arginine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in L-arginine biosynthetic process via ornithine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-arginine biosynthetic process via ornithine NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in citrulline biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in citrulline biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in citrulline biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in ornithine metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
ornithine carbamoyltransferase ArgI
NP_418675.1

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4477307..4478311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418675.1 ornithine carbamoyltransferase ArgI

    See identical proteins and their annotated locations for NP_418675.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376FPU1
    Conserved Domains (1) summary
    PRK03515
    Location:1 → 334
    PRK03515; ornithine carbamoyltransferase subunit I; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.