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treC trehalose-6-phosphate hydrolase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948762, updated on 23-Apr-2026
Official Symbol
treC
Official Full Name
trehalose-6-phosphate hydrolase
Primary source
ECOCYC:EG11402
Locus tag
b4239
See related
ASAP:ABE-0013870
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4234; olgH; treE
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Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (4463054..4464709, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene anaerobic ribonucleoside-triphosphate reductase activating protein Neighboring gene anaerobic ribonucleoside-triphosphate reductase Neighboring gene trehalose-specific PTS enzyme IIBC component Neighboring gene DNA-binding transcriptional repressor TreR

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A possible glycine radical in anaerobic ribonucleotide reductase from Escherichia coli: nucleotide sequence of the cloned nrdD gene. Sun X, et al. Proc Natl Acad Sci U S A, 1993 Jan 15. PMID 8421692, Free PMC Article
  2. Characterization of TreR, the major regulator of the Escherichia coli trehalose system. Horlacher R, et al. J Biol Chem, 1997 May 16. PMID 9148912
  3. Transport and metabolism of trehalose in Escherichia coli and Salmonella typhimurium. Maréchal LR. Arch Microbiol, 1984 Jan. PMID 6370169
  4. Trehalose metabolism in Escherichia coli: stress protection and stress regulation of gene expression. Strøm AR, et al. Mol Microbiol, 1993 Apr. PMID 8391102
  5. Molecular analysis of treB encoding the Escherichia coli enzyme II specific for trehalose. Klein W, et al. J Bacteriol, 1995 Jul. PMID 7608078, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alpha,alpha-phosphotrehalase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alpha,alpha-phosphotrehalase activity IEA
Inferred from Electronic Annotation
more info
  
enables alpha-amylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in carbohydrate catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in oligosaccharide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in trehalose catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within trehalose catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
trehalose-6-phosphate hydrolase
NP_418660.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4463054..4464709 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418660.1 trehalose-6-phosphate hydrolase

    See identical proteins and their annotated locations for NP_418660.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S7EIY4
    Conserved Domains (1) summary
    PRK10933
    Location:1 → 551
    PRK10933; trehalose-6-phosphate hydrolase; Provisional
Nucleotide Protein
Heading Accession and Version

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