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treB trehalose-specific PTS enzyme IIBC component [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948761, updated on 6-Jul-2026
Official Symbol
treB
Official Full Name
trehalose-specific PTS enzyme IIBC component
Primary source
ECOCYC:EG12127
Locus tag
b4240
See related
ASAP:ABE-0013872
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4235
Summary
[More information is available at EcoCyc: EG12127].
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Sequence:
NC_000913.3 (4464759..4466180, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene anaerobic ribonucleoside-triphosphate reductase Neighboring gene trehalose-6-phosphate hydrolase Neighboring gene DNA-binding transcriptional repressor TreR Neighboring gene leader peptide MgtL

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Characterization of TreR, the major regulator of the Escherichia coli trehalose system. Horlacher R, et al. J Biol Chem, 1997 May 16. PMID 9148912
  2. Protein:Protein interactions in the cytoplasmic membrane apparently influencing sugar transport and phosphorylation activities of the e. coli phosphotransferase system. Aboulwafa M, et al. PLoS One, 2019. PMID 31751341, Free PMC Article
  3. Trehalase of Escherichia coli. Mapping and cloning of its structural gene and identification of the enzyme as a periplasmic protein induced under high osmolarity growth conditions. Boos W, et al. J Biol Chem, 1987 Sep 25. PMID 2820965
  4. Transport and metabolism of trehalose in Escherichia coli and Salmonella typhimurium. Maréchal LR. Arch Microbiol, 1984 Jan. PMID 6370169
  5. Trehalose transport and metabolism in Escherichia coli. Boos W, et al. J Bacteriol, 1990 Jun. PMID 2160944, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein-phosphocysteine-trehalose phosphotransferase system transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-phosphocysteine-trehalose phosphotransferase system transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein-phosphocysteine-trehalose phosphotransferase system transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein-phosphocysteine-trehalose phosphotransferase system transporter activity ISM
Inferred from Sequence Model
more info
 PubMed 
enables trehalose transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within trehalose transport EXP
Inferred from Experiment
more info
 PubMed 
involved_in trehalose transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within trehalose transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in trehalose transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Preferred Names
trehalose-specific PTS enzyme IIBC component
NP_418661.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4464759..4466180 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418661.1 trehalose-specific PTS enzyme IIBC component

    See identical proteins and their annotated locations for NP_418661.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A7ZVC1
    Conserved Domains (1) summary
    PRK11007
    Location:1 → 473
    PRK11007; PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional
Nucleotide Protein
Heading Accession and Version

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