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chpS ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948739, updated on 17-Dec-2024

Summary

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Official Symbol
chpS
Official Full Name
ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system
Primary source
ECOCYC:EG11250
Locus tag
b4224
See related
ASAP:ABE-0013820
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
chpBI; ECK4220; yjfB
Summary
ChpS is the antitoxin component of the ChpB-ChpS toxin-antitoxin system. [More information is available at EcoCyc: EG11250].
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Genomic context

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Sequence:
NC_000913.3 (4448447..4448698)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene translocation and assembly module subunit TamA Neighboring gene translocation and assembly module subunit TamB Neighboring gene gamma-glutamylamine cyclotransferase family protein YtfP Neighboring gene endoribonuclease toxin ChpB Neighboring gene inorganic pyrophosphatase Neighboring gene galactofuranose ABC transporter periplasmic binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of ChpBK, an mRNA interferase from Escherichia coli. Zhang Y, et al. J Biol Chem, 2005 Jul 15. PMID 15901733
  2. Functional interactions between chpB and parD, two homologous conditional killer systems found in the Escherichia coli chromosome and in plasmid R1. Santos Sierra S, et al. FEMS Microbiol Lett, 1998 Nov 1. PMID 9812362
  3. Mapping and disruption of the chpB locus in Escherichia coli. Masuda Y, et al. J Bacteriol, 1994 Sep. PMID 8083180, Free PMC Article
  4. Structural analysis of the ileR locus of Escherichia coli K12. Weiss DL, et al. J Biol Chem, 1986 Jul 25. PMID 3525538
  5. Toxin-antitoxin modules may regulate synthesis of macromolecules during nutritional stress. Gerdes K. J Bacteriol, 2000 Feb. PMID 10633087, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables toxin sequestering activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of growth NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in single-species biofilm formation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of toxin-antitoxin complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4448447..4448698
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418645.2 ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418645.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A192CH25, A0AAN4ADS0
    Conserved Domains (1) summary
    PRK11347
    Location:1 → 83
    PRK11347; antitoxin ChpS; Provisional
Nucleotide Protein
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