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ytfK stringent response modulator YtfK [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948736, updated on 17-Jul-2025
Official Symbol
ytfK
Official Full Name
stringent response modulator YtfK
Primary source
ECOCYC:G7872
Locus tag
b4217
See related
ASAP:ABE-0013797
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4213
Summary
PhoB regulon (Baek, 2006). [More information is available at EcoGene: EG12511]. Expression of ytfK is activated by PhoB . [More information is available at EcoCyc: G7872].
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Sequence:
NC_000913.3 (4439587..4439793)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YtfI Neighboring gene PF09695 family protein YtfJ Neighboring gene putative cadaverine/putrescine exporter Neighboring gene methionine sulfoxide reductase A

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Involvement of the ytfK gene from the PhoB regulon in stationary-phase H2O2 stress tolerance in Escherichia coli. Iwadate Y, et al. Microbiology (Reading), 2017 Dec. PMID 29148366
  2. YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli. Germain E, et al. Nat Commun, 2019 Dec 17. PMID 31848343, Free PMC Article
  3. Novel gene members in the Pho regulon of Escherichia coli. Baek JH, et al. FEMS Microbiol Lett, 2006 Nov. PMID 17020555
  4. SigmaS-dependent gene expression at the onset of stationary phase in Escherichia coli: function of sigmaS-dependent genes and identification of their promoter sequences. Lacour S, et al. J Bacteriol, 2004 Nov. PMID 15489429, Free PMC Article
  5. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to phosphate starvation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within stringent response IGI
Inferred from Genetic Interaction
more info
 PubMed 
Preferred Names
stringent response modulator YtfK

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4439587..4439793
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418638.2 stringent response modulator YtfK

    See identical proteins and their annotated locations for NP_418638.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0H3JIS0, A0AAJ3NXC6, C3SFI2
    Conserved Domains (1) summary
    pfam06526
    Location:1 → 63
    DUF1107; Protein of unknown function (DUF1107)
Nucleotide Protein
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