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ulaA L-ascorbate specific PTS enzyme IIC component [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948717, updated on 30-Jul-2025
Official Symbol
ulaA
Official Full Name
L-ascorbate specific PTS enzyme IIC component
Primary source
ECOCYC:G7856
Locus tag
b4193
See related
ASAP:ABE-0013723
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4189; sgaT; yjfS
Summary
The ula divergon is comprised of the two divergent ulaGR and ulaABCDEF operons. [More information is available at EcoGene: EG12493]. UlaA is required for the ability to utilize L-ascorbate as the carbon source under anaerobic growth conditions . [More information is available at EcoCyc: G7856].
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Sequence:
NC_000913.3 (4419980..4421377)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene carboxylesterase Neighboring gene DNA-binding transcriptional repressor UlaR Neighboring gene L-ascorbate-6-phosphate lactonase Neighboring gene L-ascorbate specific PTS enzyme IIB component Neighboring gene L-ascorbate specific PTS enzyme IIA component

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The V-motifs facilitate the substrate capturing step of the PTS elevator mechanism. Vastermark A, et al. J Struct Biol, 2016 Dec. PMID 27720943, Free PMC Article
  2. Investigation into the resistance of lactoperoxidase tolerant Escherichia coli mutants to different forms of oxidative stress. De Spiegeleer P, et al. FEMS Microbiol Lett, 2005 Nov 15. PMID 16209909
  3. Bioinformatic analyses of the bacterial L-ascorbate phosphotransferase system permease family. Hvorup R, et al. J Mol Microbiol Biotechnol, 2003. PMID 15153772
  4. Is the ribulose monophosphate pathway widely distributed in bacteria? Reizer J, et al. Microbiology (Reading), 1997 Aug. PMID 9274005
  5. The ascorbate transporter of Escherichia coli. Zhang Z, et al. J Bacteriol, 2003 Apr. PMID 12644495, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-ascorbic acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within L-ascorbic acid transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within L-ascorbic acid transmembrane transport IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in L-ascorbic acid transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of transmembrane transporter complex NAS
Non-traceable Author Statement
more info
 PubMed 
Preferred Names
L-ascorbate specific PTS enzyme IIC component
NP_418614.4

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4419980..4421377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418614.4 L-ascorbate specific PTS enzyme IIC component

    See identical proteins and their annotated locations for NP_418614.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376RS91, A0A8T5YLU5
    Conserved Domains (1) summary
    PRK09548
    Location:1 → 462
    PRK09548; PTS ascorbate-specific subunit IIBC
Nucleotide Protein
Heading Accession and Version

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