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hfq RNA-binding protein Hfq [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948689, updated on 24-Jul-2021

Summary

Gene symbol
hfq
Gene description
RNA-binding protein Hfq
Primary source
ASAP:ABE-0013659
Locus tag
b4172
See related
ECOCYC:EG10438
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4168
Summary
The C-terminal of Hfq is not necessary for hexamerization. [More information is available at EcoGene: EG10438]. Hfq is an RNA-binding protein that stimulates RNA-RNA pairing and affects many cellular processes, similar to mammalian Sm/Sm-like proteins . [More information is available at EcoCyc: EG10438].
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Genomic context

Sequence:
NC_000913.3 (4400288..4400596)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene N-acetylmuramoyl-L-alanine amidase B Neighboring gene DNA mismatch repair protein MutL Neighboring gene tRNA dimethylallyltransferase Neighboring gene ribosome rescue factor HflX Neighboring gene regulator of FtsH protease

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables bent DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4400288..4400596
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418593.1 RNA-binding protein Hfq [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418593.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A6X3
    Conserved Domains (1) summary
    PRK00395
    Location:176
    hfq; RNA-binding protein Hfq; Provisional
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