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amiB N-acetylmuramoyl-L-alanine amidase B [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948683, updated on 19-Sep-2024

Summary

Official Symbol
amiB
Official Full Name
N-acetylmuramoyl-L-alanine amidase B
Primary source
ECOCYC:EG11363
Locus tag
b4169
See related
ASAP:ABE-0013653
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4165; yjeD
Summary
First 22 aa are predicted to be a type I signal peptide. [More information is available at EcoGene: EG11363]. Escherichia coli contains three N-acetylmuramyl-L-alanine amidases named AmiA, B, and C involved in cell division by splitting the murein septum. [More information is available at EcoCyc: EG11363].
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Genomic context

Sequence:
NC_000913.3 (4396065..4397402)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YjeV Neighboring gene epoxyqueuosine reductase Neighboring gene NAD(P)HX epimerase/NAD(P)HX dehydratase Neighboring gene N(6)-L-threonylcarbamoyladenine synthase, TsaE subunit Neighboring gene DNA mismatch repair protein MutL Neighboring gene tRNA dimethylallyltransferase Neighboring gene RNA-binding protein Hfq

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables N-acetylmuramoyl-L-alanine amidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables N-acetylmuramoyl-L-alanine amidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables N-acetylmuramoyl-L-alanine amidase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in FtsZ-dependent cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within FtsZ-dependent cytokinesis IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within cell division EXP
Inferred from Experiment
more info
PubMed 
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
 
involved_in peptidoglycan catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in outer membrane-bounded periplasmic space RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
N-acetylmuramoyl-L-alanine amidase B
NP_418590.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4396065..4397402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418590.1 N-acetylmuramoyl-L-alanine amidase B [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418590.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5ZBW8
    Conserved Domains (1) summary
    PRK10431
    Location:1445
    PRK10431; N-acetylmuramoyl-l-alanine amidase II; Provisional