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frdD fumarate reductase membrane protein FrdD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948668, updated on 4-Feb-2026
Official Symbol
frdD
Official Full Name
fumarate reductase membrane protein FrdD
Primary source
ECOCYC:EG10333
Locus tag
b4151
See related
ASAP:ABE-0013595
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4147
Summary
This is one of two membrane proteins in the four subunit enzyme. [More information is available at EcoCyc: EG10333].
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Sequence:
NC_000913.3 (4379007..4379366, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene guanidinium exporter Neighboring gene outer membrane lipocalin protein Neighboring gene beta-lactamase Neighboring gene fumarate reductase membrane protein FrdC Neighboring gene fumarate reductase Neighboring gene fumarate reductase flavoprotein subunit

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Oxidation of reduced menaquinone by the fumarate reductase complex in Escherichia coli requires the hydrophobic FrdD peptide. Cecchini G, et al. Proc Natl Acad Sci U S A, 1986 Dec. PMID 3538014, Free PMC Article
  2. Electron transfer from menaquinol to fumarate. Fumarate reductase anchor polypeptide mutants of Escherichia coli. Westenberg DJ, et al. J Biol Chem, 1990 Nov 15. PMID 2246242
  3. Reconstitution of quinone reduction and characterization of Escherichia coli fumarate reductase activity. Cecchini G, et al. J Biol Chem, 1986 Feb 5. PMID 3511050
  4. A mutant of Escherichia coli fumarate reductase decoupled from electron transport. Weiner JH, et al. Proc Natl Acad Sci U S A, 1986 Apr. PMID 3008149, Free PMC Article
  5. Reversible electrochemistry of fumarate reductase immobilized on an electrode surface. Direct voltammetric observations of redox centers and their participation in rapid catalytic electron transport. Sucheta A, et al. Biochemistry, 1993 May 25. PMID 8499449

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables succinate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anaerobic electron transport chain NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in anaerobic respiration EXP
Inferred from Experiment
more info
 PubMed 
involved_in anaerobic respiration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within bacterial-type flagellum assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in fumarate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of fumarate reductase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of fumarate reductase complex IEA
Inferred from Electronic Annotation
more info
  
part_of fumarate reductase complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
fumarate reductase membrane protein FrdD
NP_418575.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4379007..4379366 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418575.1 fumarate reductase membrane protein FrdD

    See identical proteins and their annotated locations for NP_418575.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7A7F5B5, A0A8S7CNA2
    Conserved Domains (1) summary
    PRK05470
    Location:2 → 119
    PRK05470; fumarate reductase subunit FrdD
Nucleotide Protein
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