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cutA copper binding protein CutA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948660, updated on 10-Oct-2024

Summary

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Official Symbol
cutA
Official Full Name
copper binding protein CutA
Primary source
ECOCYC:EG12177
Locus tag
b4137
See related
ASAP:ABE-0013544
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
cutA1; ECK4131
Summary
CutA is a copper-binding protein that is also required for copper tolerance. [More information is available at EcoCyc: EG12177].
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Genomic context

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Sequence:
NC_000913.3 (4365018..4365356, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Phe Neighboring gene putative DNA-binding transcriptional regulator YjdC Neighboring gene thiol-disulfide exchange protein DsbD Neighboring gene C4-dicarboxylate transporter DcuA Neighboring gene ncRNA Neighboring gene aspartate ammonia-lyase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Remarkable improvement in the heat stability of CutA1 from Escherichia coli by rational protein design. Matsuura Y, et al. J Biochem, 2010 Oct. PMID 20639520
  2. Protonless 13C direct detection NMR: characterization of the 37 kDa trimeric protein CutA1. Bertini I, et al. Proteins, 2008 Mar. PMID 17847095
  3. Hyper-thermostability of CutA1 protein, with a denaturation temperature of nearly 150 degrees C. Tanaka T, et al. FEBS Lett, 2006 Jul 24. PMID 16831434
  4. A mutation blocking the formation of membrane or periplasmic endogenous and exogenous c-type cytochromes in Escherichia coli permits the cytoplasmic formation of Hydrogenobacter thermophilus holo cytochrome c552. Sambongi Y, et al. FEBS Lett, 1994 May 16. PMID 8187885
  5. A reassessment of the range of c-type cytochromes synthesized by Escherichia coli K-12. Iobbi-Nivol C, et al. FEMS Microbiol Lett, 1994 Jun 1. PMID 8039676

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that the stability of Escherichia coli CutA1 is remarkably improved by slight substitutions, and that remarkable improvements in stability can be quantitatively explained based on the newly solved native structure.
    Title: Remarkable improvement in the heat stability of CutA1 from Escherichia coli by rational protein design.
  2. structural characterization of CutA1 in solution by NMR
    Title: Protonless 13C direct detection NMR: characterization of the 37 kDa trimeric protein CutA1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables copper ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables copper ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within response to copper ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to metal ion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
copper binding protein CutA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4365018..4365356 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418560.1 copper binding protein CutA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418560.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3HXS3, A0A1X3J6U0, A0A1X3J927, A0AAP7VQS5
    Conserved Domains (1) summary
    PRK10645
    Location:1 → 112
    PRK10645; divalent cation tolerance protein CutA
Nucleotide Protein
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