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dcuB anaerobic C4-dicarboxylate transporter DcuB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948641, updated on 26-Jun-2024

Summary

Gene symbol
dcuB
Gene description
anaerobic C4-dicarboxylate transporter DcuB
Primary source
ASAP:ABE-0013503
Locus tag
b4123
See related
ECOCYC:EG10006
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4116; genF
Summary
IT (Ion Transporter) superfamily (Prakash, 2003). [More information is available at EcoGene: EG10006]. The DcuB transporter is one of three transporters known to be responsible for the uptake of C4-dicarboxylates such as fumarate under anaerobic conditions. [More information is available at EcoCyc: EG10006].
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Genomic context

Sequence:
NC_000913.3 (4347404..4348744, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2238 domain-containing inner membrane protein YjdF Neighboring gene fumarase B Neighboring gene DNA-binding transcriptional activator DcuR Neighboring gene sensor histidine kinase DcuS Neighboring gene PF06902 family protein YjdI

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables C4-dicarboxylate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables C4-dicarboxylate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables succinate:fumarate antiporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within C4-dicarboxylate transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in C4-dicarboxylate transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within anaerobic respiration EXP
Inferred from Experiment
more info
PubMed 
involved_in fumarate transport IEA
Inferred from Electronic Annotation
more info
 
involved_in succinate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
anaerobic C4-dicarboxylate transporter DcuB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4347404..4348744 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418547.1 anaerobic C4-dicarboxylate transporter DcuB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418547.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7D7KDE4, A0A8S7JZC2
    Conserved Domains (1) summary
    PRK12489
    Location:38444
    PRK12489; anaerobic C4-dicarboxylate transporter; Reviewed