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melR DNA-binding transcriptional dual regulator MelR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948637, updated on 30-Jul-2025
Official Symbol
melR
Official Full Name
DNA-binding transcriptional dual regulator MelR
Primary source
ECOCYC:EG11230
Locus tag
b4118
See related
ASAP:ABE-0013486
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4111
Summary
The C-terminal domain of the RNA polymerase alpha subunit is important for MelR-dependent activation of the melAB promoter. [More information is available at EcoGene: EG11230].
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Sequence:
NC_000913.3 (4340720..4341628, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator AdiY Neighboring gene arginine decarboxylase, degradative Neighboring gene alpha-galactosidase Neighboring gene melibiose:H(+)/Na(+)/Li(+) symporter

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional dual regulator MelR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4340720..4341628 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418542.1 DNA-binding transcriptional dual regulator MelR

    See identical proteins and their annotated locations for NP_418542.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2W6P8T4, A0A376FSX3, A0A6C9JP05
    Conserved Domains (1) summary
    PRK10371
    Location:1 → 302
    PRK10371; transcriptional regulator MelR
Nucleotide Protein
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