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phnD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948624, updated on 11-Sep-2024

Summary

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Official Symbol
phnD
Primary source
ECOCYC:EG10714
Locus tag
b4105
See related
ASAP:ABE-0013442
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4098; phn; psiD
Summary
Phosphonate utilization is cryptic in K-12. [More information is available at EcoGene: EG10714]. PhnD is the periplasmic binding component of the alkylphosphonate ABC transporter. [More information is available at EcoCyc: EG10714].
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Genomic context

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Sequence:
NC_000913.3 (4323336..4324352, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transcriptional regulator PhnF Neighboring gene pseudo Neighboring gene phosphonate/phosphate ABC transporter ATP binding subunit Neighboring gene PF06983 family protein YjdN

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors. Alicea I, et al. J Mol Biol, 2011 Dec 2. PMID 22019591, Free PMC Article
  2. phnE and glpT genes enhance utilization of organophosphates in Escherichia coli K-12. Elashvili I, et al. Appl Environ Microbiol, 1998 Jul. PMID 9647836, Free PMC Article
  3. Involvement of the phosphate regulon and the psiD locus in carbon-phosphorus lyase activity of Escherichia coli K-12. Wackett LP, et al. J Bacteriol, 1987 Apr. PMID 3549702, Free PMC Article
  4. Reversible phase variation in the phnE gene, which is required for phosphonate metabolism in Escherichia coli K-12. Iqbal S, et al. J Bacteriol, 2004 Sep. PMID 15342581, Free PMC Article
  5. Sequence relationships between integral inner membrane proteins of binding protein-dependent transport systems: evolution by recurrent gene duplications. Saurin W, et al. Protein Sci, 1994 Feb. PMID 8003968, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. structural analysis of Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors
    Title: Structure of the Escherichia coli phosphonate binding protein PhnD and rationally optimized phosphonate biosensors.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
involved_in organic phosphonate transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
  
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
phosphonate/phosphate ABC transporter periplasmic binding protein
NP_418529.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4323336..4324352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418529.1 phosphonate/phosphate ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418529.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7TST9
    Conserved Domains (1) summary
    cd13575
    Location:28 → 284
    PBP2_PnhD; Substrate binding domain of ABC-type phosphonate uptake system; contains the type 2 periplasmic binding fold
Nucleotide Protein
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Gene LinkOut

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