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phnG carbon-phosphorus lyase core complex subunit PhnG [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948618, updated on 4-Feb-2026
Official Symbol
phnG
Official Full Name
carbon-phosphorus lyase core complex subunit PhnG
Primary source
ECOCYC:EG10716
Locus tag
b4101
See related
ASAP:ABE-0013433
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4094
Summary
Phosphonate utilization is cryptic in K-12. [More information is available at EcoGene: EG10716]. PhnG appears to be a component of a carbon-phosphorous lyase enzyme. phnGis part of an operon that is phosphate starvation-inducible and required for use of phosphonate and phosphite as phosphorous sources . [More information is available at EcoCyc: EG10716].
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Sequence:
NC_000913.3 (4321244..4321696, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene carbon-phosphorus lyase ATP-binding protein PhnK Neighboring gene carbon-phosphorus lyase core complex subunit PhnJ Neighboring gene carbon-phosphorus lyase core complex subunit PhnI Neighboring gene carbon-phosphorus lyase core complex subunit PhnH Neighboring gene putative transcriptional regulator PhnF Neighboring gene pseudo

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structures of the Carbon-Phosphorus Lyase Complex Reveal the Binding Mode of the NBD-like PhnK. Yang K, et al. Structure, 2016 Jan 5. PMID 26724995, Free PMC Article
  2. Subunit Interactions within the Carbon-Phosphorus Lyase Complex from Escherichia coli. Ren Z, et al. Biochemistry, 2015 Jun 2. PMID 25954983, Free PMC Article
  3. Mapping and molecular cloning of the phn (psiD) locus for phosphonate utilization in Escherichia coli. Wanner BL, et al. J Bacteriol, 1990 Mar. PMID 2155195, Free PMC Article
  4. Phosphate-independent expression of the carbon-phosphorus lyase activity of Escherichia coli. Yakovleva GM, et al. Appl Microbiol Biotechnol, 1998 May. PMID 9650256
  5. Structural insights into the bacterial carbon-phosphorus lyase machinery. Seweryn P, et al. Nature, 2015 Sep 3. PMID 26280334, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within organic phosphonate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in organic phosphonate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in organic phosphonate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in organic phosphonate transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in organic phosphonate transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of carbon phosphorus lyase complex IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
carbon-phosphorus lyase core complex subunit PhnG

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4321244..4321696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418525.1 carbon-phosphorus lyase core complex subunit PhnG

    See identical proteins and their annotated locations for NP_418525.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S7CNS0
    Conserved Domains (1) summary
    COG3624
    Location:1 → 149
    PhnG; Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [Inorganic ion transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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