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hybB hydrogenase 2 membrane subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948615, updated on 6-May-2021

Summary

Gene symbol
hybB
Gene description
hydrogenase 2 membrane subunit
Primary source
ASAP:ABE-0009830
Locus tag
b2995
See related
ECOCYC:EG11800
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2989
Summary
The HybB protein is predicted to be an integral membrane component of hydrogenase 2 . [More information is available at EcoCyc: EG11800].
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Genomic context

Sequence:
NC_000913.3 (3142986..3144164, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase maturation protein HybF Neighboring gene hydrogenase 2-specific chaperone Neighboring gene hydrogenase 2 maturation protease Neighboring gene hydrogenase 2 large subunit Neighboring gene hydrogenase 2 iron-sulfur protein Neighboring gene hydrogenase 2 small subunit Neighboring gene DUF2623 domain-containing protein YghW

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables formate dehydrogenase (quinone) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables hydrogenase (acceptor) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables hydrogenase (acceptor) activity IMP
Inferred from Mutant Phenotype
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in anaerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within anaerobic respiration IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within anaerobic respiration IMP
Inferred from Mutant Phenotype
more info
 
involved_in formate oxidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of [Ni-Fe] hydrogenase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of [Ni-Fe] hydrogenase complex IDA
Inferred from Direct Assay
more info
 
part_of formate dehydrogenase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
hydrogenase 2 membrane subunit
NP_417469.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3142986..3144164 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417469.1 hydrogenase 2 membrane subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417469.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P37180
    Conserved Domains (1) summary
    PRK10881
    Location:1392
    PRK10881; Ni/Fe-hydrogenase cytochrome b subunit
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