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alsE D-allulose-6-phosphate 3-epimerase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948595, updated on 26-Mar-2025
Official Symbol
alsE
Official Full Name
D-allulose-6-phosphate 3-epimerase
Primary source
ECOCYC:EG11957
Locus tag
b4085
See related
ASAP:ABE-0013382
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4078; yjcU
Summary
Allulose-6-phosphate 3-epimerase catalyzes the final step in the degradation of D-allose, the conversion of D-allulose-6-phosphate to D-fructose-6-phosphate, which feeds into the glycolysis pathway . [More information is available at EcoCyc: EG11957].
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Sequence:
NC_000913.3 (4307783..4308478, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative lipoprotein YtcA Neighboring gene linear primary-alkylsulfatase Neighboring gene D-allose kinase Neighboring gene D-allose ABC transporter membrane subunit Neighboring gene D-allose ABC transporter ATP binding subunit Neighboring gene D-allose ABC transporter periplasmic binding protein

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. D-Allose catabolism of Escherichia coli: involvement of alsI and regulation of als regulon expression by allose and ribose. Poulsen TS, et al. J Bacteriol, 1999 Nov. PMID 10559180, Free PMC Article
  2. Structural basis for substrate specificity in phosphate binding (beta/alpha)8-barrels: D-allulose 6-phosphate 3-epimerase from Escherichia coli K-12. Chan KK, et al. Biochemistry, 2008 Sep 9. PMID 18700786, Free PMC Article
  3. The D-allose operon of Escherichia coli K-12. Kim C, et al. J Bacteriol, 1997 Dec. PMID 9401019, Free PMC Article
  4. Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes. Blattner FR, et al. Nucleic Acids Res, 1993 Nov 25. PMID 8265357, Free PMC Article
  5. Large-scale identification of protein-protein interaction of Escherichia coli K-12. Arifuzzaman M, et al. Genome Res, 2006 May. PMID 16606699, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables D-ribulose-phosphate 3-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables allulose 6-phosphate 3-epimerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables allulose 6-phosphate 3-epimerase activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables racemase and epimerase activity, acting on carbohydrates and derivatives IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-allose catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within D-allose catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in carbohydrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in carbohydrate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in pentose-phosphate shunt, non-oxidative branch IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
D-allulose-6-phosphate 3-epimerase

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4307783..4308478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418509.1 D-allulose-6-phosphate 3-epimerase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418509.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H2VET7, Q1R3H5
    Conserved Domains (1) summary
    PRK09722
    Location:1 → 227
    PRK09722; allulose-6-phosphate 3-epimerase; Provisional
Nucleotide Protein
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