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mtn 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948542, updated on 9-Mar-2022

Summary

Gene symbol
mtn
Gene description
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Primary source
ASAP:ABE-0000545
Locus tag
b0159
See related
ECOCYC:EG11090
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0158; mtnN; pfs; yadA
Summary
Mutants accumulate 5'-deoxyadenosine and have impaired biotin synthase activity. [More information is available at EcoGene: EG11090]. The mtn gene encodes 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase . [More information is available at EcoCyc: EG11090].
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Genomic context

Sequence:
NC_000913.3 (178455..179153, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YadW Neighboring gene iron-sulfur cluster insertion protein ErpA Neighboring gene PF03458 family protein YadS Neighboring gene vitamin B12 ABC transporter periplasmic binding protein Neighboring gene dGTP triphosphohydrolase Neighboring gene periplasmic serine endoprotease DegP

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables adenosylhomocysteine nucleosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables adenosylhomocysteine nucleosidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables adenosylhomocysteine nucleosidase activity IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables methylthioadenosine nucleosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables methylthioadenosine nucleosidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables methylthioadenosine nucleosidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
NP_414701.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    178455..179153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414701.1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414701.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AF12
    Conserved Domains (1) summary
    PRK05584
    Location:1230
    PRK05584; 5'-methylthioadenosine/adenosylhomocysteine nucleosidase