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rhaS DNA-binding transcriptional activator RhaS [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948397, updated on 4-Feb-2026
Official Symbol
rhaS
Official Full Name
DNA-binding transcriptional activator RhaS
Primary source
ECOCYC:EG10843
Locus tag
b3905
See related
ASAP:ABE-0012745
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3898; rhaC2
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Sequence:
NC_000913.3 (4097736..4098572)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene rhamnulose-1-phosphate aldolase Neighboring gene L-rhamnose isomerase Neighboring gene rhamnulokinase Neighboring gene DNA-binding transcriptional activator RhaR Neighboring gene rhamnose/lyxose:H(+) symporter Neighboring gene superoxide dismutase (Mn)

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genetic evidence that transcription activation by RhaS involves specific amino acid contacts with sigma 70. Bhende PM, et al. J Bacteriol, 2000 Sep. PMID 10940041, Free PMC Article
  2. Linker regions of the RhaS and RhaR proteins. Kolin A, et al. J Bacteriol, 2007 Jan. PMID 17071764, Free PMC Article
  3. Transcription from the rha operon psr promoter. Tobin JF, et al. J Mol Biol, 1990 Jan 5. PMID 1688950
  4. Purification and properties of RhaR, the positive regulator of the L-rhamnose operons of Escherichia coli. Tobin JF, et al. J Mol Biol, 1990 Jan 5. PMID 2405166
  5. Amino acid-DNA contacts by RhaS: an AraC family transcription activator. Bhende PM, et al. J Bacteriol, 1999 Sep. PMID 10464186, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results indicate that RhaS negative autoregulation involves RhaS competition with RhaR for binding to the RhaR binding site at rhaSR.
    Title: The AraC/XylS family activator RhaS negatively autoregulates rhaSR expression by preventing cyclic AMP receptor protein activation.
  2. Results show that DNA-binding domains of RhaS (RhaS-CTD)contains all of the determinants necessary for transcription activation by RhaS.
    Title: Transcription activation by the DNA-binding domain of the AraC family protein RhaS in the absence of its effector-binding domain.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in hexose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional activator RhaS

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4097736..4098572
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418341.1 DNA-binding transcriptional activator RhaS

    See identical proteins and their annotated locations for NP_418341.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A377B6B2
    Conserved Domains (1) summary
    PRK13503
    Location:1 → 278
    PRK13503; HTH-type transcriptional activator RhaS
Nucleotide Protein
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