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fdoH formate dehydrogenase O subunit beta [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948395, updated on 22-Sep-2022

Summary

Gene symbol
fdoH
Gene description
formate dehydrogenase O subunit beta
Primary source
ASAP:ABE-0012708
Locus tag
b3893
See related
ECOCYC:EG11857
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3886
Summary
Also known as FDH-Z. [More information is available at EcoGene: EG11857]. By similarity to the paralogous subunit of formate dehydrogenase-N, FdnH, FdoH is thought to contain four [4Fe-4S] clusters and one C-terminal transmembrane helix . [More information is available at EcoCyc: EG11857].
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Genomic context

Sequence:
NC_000913.3 (4081857..4082759, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YiiF Neighboring gene formate dehydrogenase formation protein Neighboring gene formate dehydrogenase O subunit gamma Neighboring gene formate dehydrogenase O subunit alpha Neighboring gene sulfurtransferase for molybdenum cofactor sulfuration

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables formate dehydrogenase (quinone) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within anaerobic respiration IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cellular respiration IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular respiration IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within formate oxidation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in formate oxidation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within respiratory electron transport chain IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
part_of formate dehydrogenase complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
formate dehydrogenase O subunit beta
NP_418329.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4081857..4082759 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418329.1 formate dehydrogenase O subunit beta [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418329.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AAJ5
    Conserved Domains (1) summary
    TIGR01582
    Location:7288
    FDH-beta; formate dehydrogenase, beta subunit, Fe-S containing